Qualification: 
Ph.D, MSc, B.Ed.
sindhushettyk@am.amrita.edu

Dr. Sindhu Shetty K. currently serves as Assistant Professor at Amrita School of Biotechnology. She pursued her M. Sc.. from Bharathiar University. 

Education

  • 2019 : Ph. D. (Microbiology)
    Bharathiar University
  • 2001 : M. Sc. (Microbiology)
    Sree Narayana Guru College, Coimbatore
  • 1999 : B. Ed. (Physical Science)
    Kannur University
  • 1997 : B. Sc. (Microbiology, Botany, Chemistry)
    Mangalore University

Position and Honors

  • Qualified State Eligibility Test (SET), in botany from Directorate of Higher Secondary Education, Kerala.

Experience and Training Relevant to the Research Project

  • Action of beta lactam antibiotics on microorganisms in hospital samples, from PSG IMS, Coimbatore.
  • Caulobacter crescentus as an exoelecricigen in Microbial Fuel cells,
  • DNA origami-A blueprint as a building block.
  • Rapid assay development for naringinase enzyme.
  • Characterization of endo-arabinase and its application for biotransformation.
  • Lytic broadcasting system using different materials and bacteriophages as lytic agents.
  • Actinomycetes and its bioactive compounds as an antibiotic on microorganisms.
  • Biomimetic approach to design an energy efficient neutral aerator.

Subjects Handled/Handling

M. Sc. /B. Sc. Research Projects

  • Have guided more than 8 M. Sc. and 12 B. Sc. projects on different themes.

Publications

Publication Type: Journal Article

Year of Publication Title

2018

A. Vijayakumar, Ajith Madhavan, Chinchu Bose, Nanjan Pandurangan, Sindhu Shetty K., Archana Palillamvedu, Megha Prasad, Dr. Sanjay Pal, and Dr. Bipin G. Nair, “Potent Chitin Synthase Inhibitors from Plants”, Current Bioactive Compounds, vol. 14, 2018.

2016

Sindhu Shetty K., Johny, A., Lekshmi, R., Silva, J. R. D., Shanmugham, S., and Madhavan, A., “Mesocarp of Terminalia catappa L.-a potential and cost effective source for the production of alpha 1, 5- l endo- arabinase”, vol. 9, pp. 222-227, 2016.[Abstract]


The fruit of Terminalia catappa L. is used as a nutrient source in the formulation of the production media for Alpha 1, 5- L Endo- Arabinase. The mesocarp promoted the production of the enzyme (% activity of 71%) when compared to the whole fruit (60.6%) and the other epicarp layers-Endocarp (26%), Kernel (28%). The incubation time required for peak production also varied with the fruit and the epicarp layers, with the kernel peaking at the earliest in the fifth day of production. The presence of endo-arabinase activity was confirmed with the azurin cross linked (AZCL) debranched arabinan assay. The study proposes a value addition to the mesocarp which is otherwise considered to be a waste material.

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2016

Sindhu Shetty K., Madhavan, A., Ben, C. S. Sreejith, Lekshmi, R., Kumar, B. S., Govind, K., Aswathy, S., and Shanmugham, S., “Alpha 1, 5- L endo-arabinanase production media formulation and optimization using cost effective substrate”, vol. 9, pp. 40-45, 2016.[Abstract]


A new, cost effective media was formulated with soy chunk powder (SCP) as the nutrient source. Growth parameters such as temperature, pH and substrate concentration were optimized. Temperature of 300C, pH of 4 and 1.5% (w/v) of substrate concentration, constitute the optimal condition for the maximal production of the enzyme. The enzyme production peaked in the 5th day of incubation with a maximal enzyme activity of 1.218 U/mg which is 42% as efficient as production in media employing pure substrate. Aspergillus niger isolated from the soil samples collected from the precincts of the campus was employed in the current study.

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2016

A. Madhavan, Pandurangan, N., Sindhu Shetty K., and Shanmugham, S., “A rapid and selective method for the quantification of naringenin in order to monitor naringinase activity”, vol. 9, pp. 333-338, 2016.[Abstract]


Sodium acetate (NaOAc) can selectively ionize 7-OH of naringenin generating a bathochromic shift of 41nm in its UV absorbance. This principle is used in the described spectrophotometric method that can detect naringenin amidst naringin and prunin present in the incubation mixture of naringinase. The method could be adopted for real sample analysis as it remains unaffected by the presence of phenolics such as ascorbic acid, gallic acid, citric acid and cinnamic acid.

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Publication Type: Conference Paper

Year of Publication Title

2017

A. Madhavan, Sindhu Shetty K., G. Anjana, A. Das, A.S. Athira, H. Hari, K. S. Lekshmi, S. Babu, Dr. Bipin G. Nair, and Dr. Sanjay Pal, “Pneumatophore inspired biomimetic approach to design an energy neutral aerator for application in composting”, in Technical Program Committee of the “2017 IEEE International ( Biennial) Conference on Technological Advancements in Power and Energy”, TAP Energy-2017. , 2017.

2017

A. Madhavan, Prasad Megha, S. Girish, Sindhu Shetty K., Dr. Bipin G. Nair, and Dr. Sanjay Pal, “Caulobacter crescentus as a novel exoelectricigen in a dual chambered Microbial Fuel Cell (MFC)”, in Technical Program Committee of the “2017 IEEE International( Biennial) Conference on Technological Advancements in Power and Energy”, TAP Energy-2017. , 2017.

2016

A. Madhavan, Vishnu Nandakumar, Sindhu Shetty K., Dr. Bipin G. Nair, and Dr. Sanjay Pal, “Optimization of microbial fuel cell (MFC) operated with waste water as substrate”, in Electrical, Electronics, and Optimization Techniques (ICEEOT), International Conference on, Chennai, India, 2016.[Abstract]


In the present study bioelectricity generation from waste water was evaluated in a double chambered microbial fuel cell (MFC). Waste water and potassium permanganate solution (0.3%) was loaded in the anodic and the cathodic chamber respectively. The performance of MFC was studied with two different electrodes (aluminum and carbon as anodes and copper as cathode). Current and voltage measurements were carried out using Keithley source meter (2420) and multimeter respectively. The Voltammetric analysis was done to study the anodic oxidation rate. The resistance of the system was found to be low (0.466 Ω for the aluminum anode and 0.673 Ω carbon anode) which were deduced from the power density curves. The system showed a COD removal of 77% over a period of a week ofk operation.

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2015

Sindhu Shetty K., “Cost effective media formulation and optimization for the production of Alpha-1, 5-endo-arabinase (Poster)”, in international symposium, Emerging Discoveries in Microbiology by 56th Annual Conference of Association of Microbiologists of India (AMI-2015), School of Life Sciences, JNU, New Delhi, 2015.

2015

Sindhu Shetty K., “Cost effective media for the production of Alpha-1, 5-endo arabinase”, in international conference, Biospectrum, MCFAST, Thiruvalla, Kerala, 2015.

Faculty Research Interest: