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Dr. Lalitha Biswas

Associate Professor ,Amrita School of Nanosciences and Molecular Medicine, Kochi

Qualification: Ph.D
lalithabiswas@aims.amrita.edu

Bio

Dr. Lalitha Biswas currently serves as Associate Professor, Molecular Biology Diagnostics Group, Amrita Centre for Nanosciences and Molecular Medicine. She joined Amrita in January 2010. She obtained her Ph.D from the University of Tuebingen, Germany. Her postdoctoral training was at University of Tuebingen, Germany and Purdue University, Indiana, USA. She was a member of the Graduate College Infection Biology (GKI-685), German Research Foundation and Sonder Forshungs Bereich (SFB). A couple of research projects on which she is currently working on is concentrated on molecular biology and Infection biology which is funded by DST and ICMR.

She adds to her achievements the author and co – author of nearly 11 publications in various reputed journals like journal of immunology, journal of Bacteriology etc. She qualified CSIR – NET in the year 2000. Apart from these she owned the DFG fellowship from 2002 – 2006 and also received the fellowship from German Sonder Forshungs Bereich for the year 2007 – 2009.

Currently, Dr. Biswas also heads the Molecular biology diagnostic laboratory, which provides diagnostic services under various categories such as histocompatability & immunogenetics, gene testing, pharmacogenomics, cancer genetics and molecular basis of infectious diseases.

 

Publications

Journal Article

Year : 2022

Describing the Clinical and Laboratory Features and HLA-B Pattern of Adult-Onset Idiopathic Autoimmune Uveitis at a Tertiary Hospital in South India: A Cross-Sectional Study

Cite this Research Publication : Jyothi Visalakshy, Sandeep Surendran, Salil Ganu, Kannisha Shah, C. B. Mithun, Vishal Marwaha, Lalitha Biswas, Niveditha Kartha, Gopale Pillai, "Describing the Clinical and Laboratory Features and HLA-B Pattern of Adult-Onset Idiopathic Autoimmune Uveitis at a Tertiary Hospital in South India: A Cross-Sectional Study", The Scientific World Journal, vol. 2022, ArticleID 5032881, 9 pages, 2022.

Publisher : The Scientific World Journal,

Year : 2021

SARS-CoV-2 antibodies in healthcare workers in a large university hospital, Kerala, India

Cite this Research Publication : A. Kumar, D. Sathyapalan, A. Ramachandran, K. Subhash, L. Biswas, K.V. Beena "SARS-CoV-2 antibodies in healthcare workers in a large university hospital, Kerala, India", Clinical Microbiology and Infection, 2021

Publisher : Clinical Microbiology and Infection,

Year : 2021

Class II HLA (DRB1, & DQB1) alleles and IL7R (rs6897932) variants and the risk for Multiple Sclerosis in Kerala, India

Cite this Research Publication : Navia Vinoy, Neethu Sheeja, Suresh Kumar, and Dr. Lalitha Biswas, “Class II HLA (DRB1, & DQB1) alleles and IL7R (rs6897932) variants and the risk for Multiple Sclerosis in Kerala, India.”, Multiple Sclerosis and Related Disorders, vol. 50, p. 102848, 2021.

Publisher : Multiple Sclerosis and Related Disorders, Volume 50, p.102848 (2021)

Year : 2021

Dirofilarial adult worms can also dance.

Cite this Research Publication : Dr. Anil Kumar V., Aswin Prabhakaran, Sanju Sherji, Dr. Lalitha Biswas, Arya Ramachandran, Mohan Abraham, and Dr. Raja Biswas, “Dirofilarial adult worms can also dance.”, Clinical Microbiology and Infection, vol. 27, pp. 1118-1119., 2021.

Publisher : Clinical Microbiology and Infection,

Year : 2021

Therapeutic applications of lysostaphin against Staphylococcus aureus

Cite this Research Publication : J. Jayakumar, V.A. Kumar, L. Biswas,R. Biswas "Therapeutic applications of lysostaphin against Staphylococcus aureus" in Journal Appl Microbiol, 2021.

Publisher : Journal of Applied Microbiology,

Year : 2021

Comparison of Phenotypic MRSA Detection Methods with PCR for mecA Gene in the Background of Emergence of Oxacillin-Susceptible MRSA

Cite this Research Publication : Deepa Nair, Nandita Shashindran, Anil Kumar, Vivek Vinodh, Lalitha Biswas, and Raja Biswas "Comparison of Phenotypic MRSA Detection Methods with PCR for mecA Gene in the Background of Emergence of Oxacillin-Susceptible MRSA", Microbial Drug Resistance, 2021

Publisher : Microbial Drug Resistance,

Year : 2021

Eosinophilic Meningitis and Intraocular Infection Caused by Dirofilaria sp. Genotype Hongkong

Cite this Research Publication : Aruna S. Jyotsna, Kollencheri Puthenveettil Vinayan, Lalitha Biswas, Sujithra Haridas, Arun G. Roy, Parasmal Suresh, and Anil Kumar "Eosinophilic Meningitis and Intraocular Infection Caused by Dirofilaria sp. Genotype Hongkong", Emerg Infect Dis Journal, 2021

Publisher : Emerg Infect Dis Journal

Year : 2021

Protective efficacy of Alum adjuvanted Amidase protein vaccine against Staphylococcus aureus infection in multiple mouse models

Cite this Research Publication : Maneesha K. Suresh,Anil Kumar Vasudevan,Lalitha Biswas,Raja Biswas "Protective efficacy of Alum adjuvanted Amidase protein vaccine against Staphylococcus aureus infection in multiple mouse models" Journal of Applied Microbiology [Internet]. 2021

Publisher : Journal of Applied Microbiology

Year : 2021

Prevalence of high-risk HPV and its genotypes-Implications in the choice of prophylactic HPV vaccine.

Cite this Research Publication : Alka Suresh, Parasmal Suresh, Dr. Raja Biswas, Anupama Rajanbabu, Sarala Sreedhar, and Dr. Lalitha Biswas, “Prevalence of high-risk HPV and its genotypes-Implications in the choice of prophylactic HPV vaccine.”, J Med Virol, vol. 93, no. 8, pp. 5188-5192, 2021.

Publisher : J Med Virol

Year : 2021

Universal screening for SARS-CoV-2 in pregnant women using a combination of antigen and RT-PCR testing.

Cite this Research Publication : Dr. Anil Kumar V., Radhamany Kunjukutty, Ameena Thaha, Saranya Srikumar, Haritha Madhusoodanan, Sachin David, Dr. Lalitha Biswas, and Dipu Sathyapalan, “Universal screening for SARS-CoV-2 in pregnant women using a combination of antigen and RT-PCR testing.”, Infezioni in Medicina, vol. 29, no. 2, pp. 294-296, 2021.

Publisher : Infezioni in Medicina

Year : 2021

Candidatus Dirofilaria Hongkongensis Infections in Humans During 2005 to 2020, in Kerala, India.

Cite this Research Publication : Dr. Anil Kumar V., Ani Sreedhar, Dr. Lalitha Biswas, Sarga Prabhat, Parasmal Suresh, Asokan, A., Rita Mary Tomy, Vivek Vinod, Bindu Lakshmanan, Ajit Nambiar, and Dr. Raja Biswas, “Candidatus Dirofilaria Hongkongensis Infections in Humans During 2005 to 2020, in Kerala, India.”, American Journal of Tropical Medicine and Hygiene, vol. 104, pp. 2046-2049., 2021.

Publisher : American Journal of Tropical Medicine and Hygiene

Year : 2021

Class II HLA (DRB1, & DQB1) alleles and IL7R (rs6897932) variants and the risk for Multiple Sclerosis in Kerala, India.

Cite this Research Publication : Navia Vinoy, Neethu Sheeja, Suresh Kumar, and Dr. Lalitha Biswas, “Class II HLA (DRB1, & DQB1) alleles and IL7R (rs6897932) variants and the risk for Multiple Sclerosis in Kerala, India.”, Multiple Sclerosis and Related Disorders, vol. 50, p. 102848, 2021.

Publisher : Multiple Sclerosis and Related Disorders

Year : 2021

Comparison of Phenotypic MRSA Detection Methods with PCR for Gene in the Background of Emergence of Oxacillin-Susceptible MRSA.

Cite this Research Publication : Deepa Nair, Nandita Shashindran, Anil kumar, Vivek Vinodh, Dr. Lalitha Biswas, and Dr. Raja Biswas, “Comparison of Phenotypic MRSA Detection Methods with PCR for Gene in the Background of Emergence of Oxacillin-Susceptible MRSA.”, Microbial Drug Resistance, vol. 27, no. 9, pp. 1190-1194, 2021.

Publisher : Microbial Drug Resistance

Year : 2021

Protective efficacy of Alum adjuvanted Amidase protein vaccine against Staphylococcus aureus infection in multiple mouse models.

Cite this Research Publication : M. K. Suresh, Vasudevan, A. K., Dr. Lalitha Biswas, and Dr. Raja Biswas, “Protective efficacy of Alum adjuvanted Amidase protein vaccine against Staphylococcus aureus infection in multiple mouse models.”, Journal of Applied Microbiology (Article in Press), 2021.

Publisher : Journal of Applied Microbiology

Year : 2021

Improving Diagnosis of Hepatitis C Virus Infection Using Hepatitis C Core Antigen Testing in a Resource-Poor Setting.

Cite this Research Publication : Ayswarya Kannan, Dr. Lalitha Biswas, Anil Kumar, Jessy Kurian, Anjaly S. Nair, Parasmal Suresh, Shine Sadasivan, and Dr. Raja Biswas, “Improving Diagnosis of Hepatitis C Virus Infection Using Hepatitis C Core Antigen Testing in a Resource-Poor Setting.”, Rev Soc Bras Med Trop, vol. 54, p. e02532020, 2021.

Publisher : Rev Soc Bras Med Trop

Year : 2020

BCG Infection due to MPT64 – Negative Strain: A Diagnostic Challenge

Cite this Research Publication : Parasmal Suresh, Lalitha Biswas, Vinitha Prasad, Anil Kumar, Suchitra Sivadas, Sadia Khan, and Raja Biswas "BCG Infection due to MPT64-Negative Strain: A Diagnostic Challenge", American Journal of Tropical Medicine Hygiene, 2021

Year : 2020

Mutation Profile of JAK2, EPOR and CALR Genes in Polycythemia Patients

Cite this Research Publication : A. A., Sidharthan, N., Vidyadharan, G., Kurian, J., and Dr. Lalitha Biswas, “Mutation Profile of JAK2, EPOR and CALR Genes in Polycythemia Patients”, Blood Cells, Molecules, and Diseases, vol. 82, p. 102414, 2020.

Publisher : Blood Cells, Molecules, and Diseases

Year : 2018

Colistin resistance due to insertional inactivation of the mgrB in Klebsiella pneumoniae of clinical origin: First report from India

Cite this Research Publication : Anil Kumar, Lalitha Biswas, Neha Omgy, Karthika Mohan, Vivek Vinod, Anjali Sajeev, Prem Nair, Sanjeev Singh, and Raja Biswas "Colistin resistance due to insertional inactivation of the mgrB in Klebsiella pneumoniae of clinical origin: First report from India", Rev Esp Quimioter, 2018

Year : 2017

Epidermal growth factor receptor (EGFR) structure-based bioactive pharmacophore models for identifying next-generation inhibitors against clinically relevant EGFR mutations.

Cite this Research Publication : P. S. Panicker, Melge, A. R., Biswas, L., Keechilat, P., and Mohan, C. G., “Epidermal growth factor receptor (EGFR) structure-based bioactive pharmacophore models for identifying next-generation inhibitors against clinically relevant EGFR mutations.”, Chem Biol Drug Des, vol. 90, no. 4, pp. 629-636, 2017.

Publisher : Chem Biol Drug Des,

Year : 2017

Lack of Association of B-type Raf Kinase V600E Mutation with High-risk Tumor Features and Adverse Outcome in Conventional and Follicular Variants of Papillary Thyroid Carcinoma

Cite this Research Publication : Dr. Lalitha Biswas, CG, N., M, B., Pradeep Jacob, Riju R. Menon, AK, R., and K, N., “Lack of Association of B-type Raf Kinase V600E Mutation with High-risk Tumor Features and Adverse Outcome in Conventional and Follicular Variants of Papillary Thyroid Carcinoma”, Indian Journal of Endocrinol Metab, vol. 21, no. 2, pp. 329-333, 2017.

Publisher : Indian Journal of Endocrinol Metab

Year : 2017

Impact of Cell Wall Peptidoglycan O-acetylation on the Pathogenesis of Staphylococcus Aureus in Septic Arthritis

Cite this Research Publication : G. Baranwal, Mohammad, M., Jarneborn, A., Reddy, B. Raghunath, Golla, A., Chakravarty, S., Biswas, L., Götz, F., Dr. Sahadev Shankarappa, Jin, T., and Dr. Raja Biswas, “Impact of Cell Wall Peptidoglycan O-acetylation on the Pathogenesis of Staphylococcus Aureus in Septic Arthritis”, Int J Med Microbiol, vol. 307, no. 7, pp. 388-397, 2017.

Publisher : Int J Med Microbiol

Year : 2017

First Two Bilateral Hand Transplantations in India (Part 4): Immediate Post-operative Care, Immunosuppression Protocol and Monitoring

Cite this Research Publication : Dr. Lalitha Biswas, S, I., M, S., P, K., J, M., R, J., R, R., A, W., ,, SM, C. Mali, V, V., A, C., S, D., A, O., G, K., R, N., A, M., Z, P., and M, E., “First Two Bilateral Hand Transplantations in India (Part 4): Immediate Post-operative Care, Immunosuppression Protocol and Monitoring”, Indian J Plast Surg, vol. 50, no. 2, pp. 168-172, 2017.

Publisher : Indian J Plast Surg

Year : 2017

Epidermal Growth Factor Receptor (EGFR) Structure-based Bioactive Pharmacophore Models for Identifying Next-generation Inhibitors Against Clinically relevant EGFR Mutations

Cite this Research Publication : P. S. Panicker, Melge, A. R., Dr. Lalitha Biswas, Keechilat, P., and Dr. Gopi Mohan C., “Epidermal Growth Factor Receptor (EGFR) Structure-based Bioactive Pharmacophore Models for Identifying Next-generation Inhibitors Against Clinically relevant EGFR Mutations”, Chemical Biology & Drug Design, vol. 90, pp. 629-636, 2017.

Publisher : Chemical Biology Drug Design

Year : 2016

Antibiotic Resistance in Pseudomonas Aeruginosa and Alternative Therapeutic Options

Cite this Research Publication : M. Chatterjee, Anju, C. P., Biswas, L., V. Kumar, A., Dr. Gopi Mohan C., and Dr. Raja Biswas, “Antibiotic Resistance in Pseudomonas Aeruginosa and Alternative Therapeutic Options”, International Journal of Medical Microbiology, vol. 306, pp. 48 - 58, 2016.

Publisher : International Journal of Medical Microbiology, Elsevier GmbH,

Year : 2016

Detection of Occult Hepatitis B and Window Period Infection Among Blood Donors by Individual donation Nucleic Acid Testing in a Tertiary Care Center in South India

Cite this Research Publication : C. S. Keechilot, Shenoy, V., A. Kumar, Dr. Lalitha Biswas, Vijayrajratnam, S., Dinesh, K., and Dr. Prem Kumar Nair, “Detection of Occult Hepatitis B and Window Period Infection Among Blood Donors by Individual donation Nucleic Acid Testing in a Tertiary Care Center in South India”, Pathogens and Global Health, pp. 1-5, 2016.

Publisher : Pathogens and Global Health, Taylor and Francis.

Year : 2015

Amidase, a Cell Wall Hydrolase, Elicits Protective Immunity Against Staphylococcus Aureus and S. Epidermidis

Cite this Research Publication : N. Nair, Vinod, V., Suresh, M. K., Vijayrajratnam, S., Dr. Lalitha Biswas, Peethambaran, R., Vasudevan, A. K., and Dr. Raja Biswas, “Amidase, a Cell Wall Hydrolase, Elicits Protective Immunity Against Staphylococcus Aureus and S. Epidermidis”, International Journal of Biological Macromolecules, vol. 77, pp. 314-321, 2015.

Publisher : International Journal of Biological Macromolecules, Elsevier

Year : 2014

Staphylococcus aureus in polymicrobial infections: impact on pathogenesis

Cite this Research Publication : N. Nair, Dr. Raja Biswas, Götz, F., and Biswas, L., “Staphylococcus aureus in polymicrobial infections: impact on pathogenesis”, Infection and Immunity, p. IAI–00059, 2014.

Publisher : Infection and Immunity, American Society for Microbiology,

Year : 2014

Autochthonous Blastomycosis of the Adrenal: First Case Report from Asia

Cite this Research Publication : Anil Kumar, Sreehari, S., Velayudhan, K., Dr. Lalitha Biswas, Babu, R., Ahmed, S., Sharma, N., Kurupath, V. P., Jojo, A., Dinesh, K. R., Karim, S., and Biswas, R., “Autochthonous Blastomycosis of the Adrenal: First Case Report from Asia”, The American Journal of Tropical Medicine and Hygiene, vol. 90, 2014.

Publisher : The American Journal of Tropical Medicine and Hygiene

Year : 2013

Innate immune recognition of microbial cell wall components and microbial strategies to evade such recognitions

Cite this Research Publication : Va Sukhithasri, Nisha, Na, Dr. Lalitha Biswas, Kumar, VbAnil, and Dr. Raja Biswas, “Innate immune recognition of microbial cell wall components and microbial strategies to evade such recognitions”, Microbiological Research, vol. 168, pp. 396-406, 2013.

Publisher : Microbiological Research

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