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Dr. Vipin A. Nair

Associate Professor, School of Biotechnology, Amritapuri

Qualification: Ph.D
vipinanair@am.amrita.edu
Research Interest: Natural product Lead Discovery, Biomolecular Chemistry, Medicinal Chemistry

Bio

Dr. Vipin Nair currently serves as Associate Professor at the School of Biotechnology. His research interests are Natural product Lead Discovery, Biomolecular Chemistry, Medicinal Chemistry.

Publications

Journal Article

Year : 2024

A Mild and Eco-friendly, One-pot Synthesis of 2-hydroxy-Narylacetamides from 2-chloro-N-arylacetamides

Cite this Research Publication : Radhakrishna , Y. Vamshikrishna,Khatik , L. Gopal,Vijaya , S. Bhuvaneshwari,Nair , A. Vipin,A Mild and Eco-friendly, One-pot Synthesis of 2-hydroxy-Narylacetamides from 2-chloro-N-arylacetamides,Letters in Organic Chemistry, volume 21, issue 5, pages 391-399, year 2024, issn 1570-1786/1875-6255, doi 10.2174/0115701786279583231124093402

Publisher : Bentham Science

Year : 2022

A convenient synthesis of 3-arylideneindolin-2-ones and evaluation of their photoelectrochemical properties

Cite this Research Publication : Vipin A. Nair*, Aiyagala M. M. Mallikarjunaswamy, Gopal L. Khatik, Prashanth Vishwa and Sakthivel Kandaiah, "A convenient synthesis of 3-arylideneindolin-2-ones and evaluation of their photoelectrochemical properties", Organic Communications 2022, 15, 261-272

Publisher : ACG Publications

Year : 2022

An efficient and ecofriendly synthesis of 3,7-diaryltetrahydro-1H,5H-[1,2,4]triazolo[1,2- α][1,2,4]triazole-1,5-dithiones

Cite this Research Publication : A. M. M. Mallikarjunaswamy, Bhuvaneshwari S Vijaya, Gopal L. Khatik, Sidharth Chopra, Abdul Akhir, Deepanshi Saxena and Vipin A. Nair*, "An efficient and ecofriendly synthesis of 3,7-diaryltetrahydro-1H,5H-[1,2,4]triazolo[1,2- α][1,2,4]triazole-1,5-dithiones", Asian Journal of Chemistry 2022, 34, 3243-3246

Publisher : Asian Publication Corporation

Year : 2020

2-Iodoxybenzoic acid: an oxidant for functional group transformations

Cite this Research Publication : Vipin A. Nair*, "2-Iodoxybenzoic acid: an oxidant for functional group transformations", Oriental Journal of Chemistry, 2020, 36, 792-803

Publisher : Oriental Scientiβic Publishing Company

Year : 2017

AlCl3/cyclohexane mediated electrophilic activation of isothiocyanates: an efβicient synthesis of thioamides

Cite this Research Publication : Kapil Kumar, Debabrata Konar, Sandeep Goyal, Mukesh Gangar, Mangilal Chouhan, Ravindra K. Rawal and Vipin A. Nair, "AlCl3/Cyclohexane Mediated Electrophilic Activation of Isothiocyanates: An Efficient Synthesis of Thioamides", Chemistry Select 2016, 1, 3228-3231

Publisher : Wiley

Year : 2017

First Stereoselective Total Synthesis of Ligraminol E

Cite this Research Publication : Mukesh Gangar, Sandeep Goyal, Vankodoth Hathiram, Wasnik Ashik Ramdas, Vajja Krishna Rao and Vipin A. Nair* "First stereoselective total synthesis of ligraminol E", Chemistry Select 2017, 2, 257-259

Publisher : Wiley

Year : 2017

An auxiliary mediated alkylation approach towards the synthesis of β-aminocarbonyl derivatives

Cite this Research Publication : Sandeep Goyal, Gaurang V. Garasiya, Mukesh Gangar, Nikitha Gaddam, Maulik N. Mungalpara, Sagar Ravso Mudshinge and Vipin A. Nair* "An auxiliary mediated alkylation approach towards the synthesis of β-aminocarbonyl derivatives", Chemistry Select 2017, 2, 745-747

Publisher : Wiley

Year : 2017

A highly efficient stereoselective synthesis of β-lactams

Cite this Research Publication : Sandeep Goyal, Anang Pal, Mangilal Chouhan, Mukesh Gangar, Sharad Sarak and Vipin A. Nair, "A highly efβicient stereoselective synthesis of β-lactams" Tetrahedron Letters 2017, 58, 346-348

Publisher : Elsevier

Year : 2017

A Highly Stereoselective Chiral Auxiliary-assisted Reductive Cyclization to Furoindoline

Cite this Research Publication : Kapil Kumar, Shital S. More, Gopal L. Khatik, Ravindra K. Rawal and Vipin A. Nair* "A highly stereoselective chiral auxiliary-assisted reductive cyclization to furoindoline", Journal of Heterocyclic Chemistry 2017, 54, 2696-2702

Publisher : Wiley

Year : 2016

A convenient synthesis of 4-alkyl-3-benzoylpyrroles from α,β-unsaturated ketones and tosylmethyl isocyanide

Cite this Research Publication : Kapil Kumar, Shital S. More, Sandeep Goyal, Mukesh Gangar, Gopal L. Khatik, Ravindra K. Rawal and Vipin A. Nair "A convenient synthesis of 4-alkyl-3-benzoylpyrroles from α,β-unsaturated ketones and tosylmethyl isocyanide", Tetrahedron Letters 2016, 57, 2315-2319

Publisher : Elsevier

Year : 2016

A highly efficient and enantioselective synthesis of EEHP and EMHP: intermediates of PPAR agonists

Cite this Research Publication : Mukesh Gangar, Harikrishnan M., Sandeep Goyal, Maulik N. Mungalpara and Vipin A. Nair, "A highly efficient and enantioselective synthesis of EEHP and EMHP: intermediates of PPAR agonists", Tetrahedron Letters 2016, 57, 3462-3467

Publisher : Elsevier

Year : 2016

ZrCl4 catalysed diastereoselective synthesis of spirocarbocyclic oxindoles via [4+2] cycloaddition

Cite this Research Publication : Kapil Kumar, Julekha Siddique, Mukesh Gangar, Sandeep Goyal, Ravindra K. Rawal and Vipin A. Nair, "ZrCl4 Catalysed Diastereoselective Synthesis of Spirocarbocyclic Oxindoles via [4+2] Cycloaddition", Chemistry Select 2016, 1, 2409-2412

Publisher : Wiley

Year : 2016

Stereoselective alkylation of imines and its application towards the synthesis of β-lactams

Cite this Research Publication : Sandeep Goyal, Anamika Thakur, Ratnesh Sharma, Mukesh Gangar, Bhautikkumar Patel and Vipin A. Nair, "Stereoselective Alkylation of Imines and its Application towards the Synthesis of β‐Lactams", Asian Journal of Organic Chemistry 2016, 5, 1359-1367

Publisher : Wiley

Year : 2016

Anti selective glycolate aldol reactions of (S)-4-isopropyl-1-[(R)-1-phenylethyl]imidazolidin-2-one: application towards the asymmetric synthesis of 8-4ꞌ-oxyneolignans

Cite this Research Publication : Mukesh Gangar, Avinash Ittuveetil, Sandeep Goyal, Anang Pal, Harikrishnan M. and Vipin A.Nair, "Anti selective glycolate aldol reactions of (S)-4-isopropyl-1-[(R)-1-phenylethyl]imidazolidin-2-one: application towards the asymmetric synthesis of 8-4ꞌ-oxyneolignans", RSC Advances 2016, 6, 102116-102126

Publisher : Royal Society of Chemistry

Year : 2016

Asymmetric glycolate alkylation approach towards the total synthesis of 8-O-6ꞌ and 8-O-4ꞌ neolignans

Cite this Research Publication : Mukesh Gangar, Mangilal Chouhan, Sandeep Goyal, Harikrishnan M., R. Chandran, Avinash Ittuvetil and Vipin A. Nair "Asymmetric glycolate alkylation approach towards the total synthesis of 8-O-6ꞌ and 8-O-4ꞌ neolignans", Tetrahedron Letters 2016, 57, 5931-5934

Publisher : Elsevier

Year : 2015

An efficient strategy for the synthesis of syn 1,3-diols via iterative acetate aldol reactions and synthesis of atorvastatin lactone

Cite this Research Publication : Sandeep Goyal, Bhautikkumar Patel, Ratnesh Sharma, Mangilal Chouhan, Kapil Kumar, Mukesh Gangar and Vipin A. Nair, "An efficient strategy for the synthesis of syn 1,3-diols via iterative acetate aldol reactions and synthesis of atorvastatin lactone", Tetrahedron Letters 2015, 56, 5409-5412

Publisher : Elsevier

Year : 2015

Zirconocene dichloride catalysed one-pot synthesis of pyrroles through nitroalkene-enamine assembly

Cite this Research Publication : Sandeep Goyal, Jatinkumar K. Patel, Mukesh Gangar, Kapil Kumar and Vipin A. Nair, "Zirconocene dichloride catalysed one-pot synthesis of pyrroles through nitroalkene-enamine assembly", RSC Advances, 2015, 5, 3187-3195

Publisher : Royal Society of Chemistry

Year : 2015

A catalyst free, one pot approach for the synthesis of quinoxaline derivatives via oxidative cyclisation of 1,2-diamines and phenacyl bromides

Cite this Research Publication : Kapil Kumar, Sagar Ravso Mudshinge, Sandeep Goyal, Mukesh Gangar and Vipin A. Nair, "A catalyst free, one pot approach for the synthesis of quinoxaline derivatives via oxidative cyclisation of 1,2-diamines and phenacyl bromides.", Tetrahedron Letters 2015, 56, 1266-1271

Publisher : Elsevier

Year : 2015

Imidazolidinone based chiral auxiliary mediated acetate aldol reactions of isatin derivatives and stereoselective synthesis of 3-substituted-3-hydroxy-2-oxindoles

Cite this Research Publication : Mukesh Gangar, Naresh Kashyap, Kapil Kumar, Sandeep Goyal and Vipin A. Nair, "Imidazolidinone based chiral auxiliary mediated acetate aldol reactions of isatin derivatives and stereoselective synthesis of 3-substituted-3-hydroxy-2-oxindoles", Tetrahedron Letters, 2015, 56, 7074-7081

Publisher : Elsevier

Year : 2014

Design and synthesis of optically pure 3-aryl-6-methyl-2-thioxotetrahydropyrimidin-4(1H)-ones as anti-prostate cancer agents

Cite this Research Publication : Varun Kumar, Mahesh Rachamalla, Prajwal Nandekar, Gopal L. Khatik, Abhay T. Sangamwar, Kulbhushan Tikoo and Vipin A. Nair "Design and synthesis of optically pure 3-aryl-6-methyl-2-thioxotetrahydropyrimidin-4(1H)-ones as anti-prostate cancer agents", RSC Advances 2014, 4, 37868-37877

Publisher : Royal Society of Chemistry

Year : 2013

Aldol reactions of 2-thioxotetrahydropyrimidin-4-(1H)-ones: stereoregulations from endo- and exocyclic chiral centres

Cite this Research Publication : Varun Kumar, Kapil Kumar, Anang Pal, Gopal L. Khatik and Vipin A. Nair, "Aldol reactions of 2-thioxotetrahydropyrimidin-4-(1H)-ones: stereoregulations from endo- and exocyclic chiral centres", Tetrahedron 2013, 69, 1747-1754

Publisher : Elsevier

Year : 2013

NiCl2·6H2O/NaBH4 in methanol: a mild and efficient strategy for chemoselective deallylation/debenzylation of aryl ethers

Cite this Research Publication : Mangilal Chouhan, Kapil Kumar, Ratnesh Sharma, Vikas Grover and Vipin A. Nair, "NiCl2.6H2O/NaBH4 in methanol: a mild and efficient strategy for chemoselective
deallylation/debenzylation of aryl ethers", Tetrahedron Letters, 2013, 54, 4540-4543

Publisher : Elsevier

Year : 2013

Stereoselective synthesis of (S)-dapoxetine: a chiral auxiliary mediated approach

Cite this Research Publication : Gopal L. Khatik, Ratnesh Sharma, Varun Kumar, Mangilal Chouhan and Vipin A. Nair, "Stereoselective synthesis of (S)-dapoxetine: a chiral auxiliary mediated approach", Tetrahedron Letters 2013, 54, 5991-5993

Publisher : Elsevier

Year : 2013

Quinine as an organocatalytic dual activator for the diastereoselective synthesis of spiroepoxyoxindoles

Cite this Research Publication : Mangilal Chouhan, Anang Pal, Ratnesh Sharma and Vipin A. Nair, "Quinine as an organocatalytic dual activator for the diastereoselective synthesis of spiroepoxyoxindoles", Tetrahedron Letters, 2013, 54, 7119-7123

Publisher : Elsevier

Year : 2013

Lithium hydroxide mediated synthesis of 3,4-disubstituted pyrroles

Cite this Research Publication : Ratnesh Sharma, Kapil Kumar, Mangilal Chouhan, Vikas Grover and Vipin A. Nair "Lithium hydroxide mediated synthesis of 3,4-disubstituted pyrroles", RSC Advances, 2013, 3, 14521-14527

Publisher : Royal Society of Chemistry

Year : 2013

Total synthesis of a pyrroloindoloquinazoline alkaloid

Cite this Research Publication : Digvijay Gahtory, Mangilal Chouhan, Ratnesh Sharma, and Vipin A. Nair "Total Synthesis of a Pyrroloindoloquinazoline Alkaloid", Organic Letters 2013, 15, 3942-3945

Publisher : American Chemical Society

Year : 2012

1,2,4-Oxadiazoles: a new class of anti-prostate cancer agents

Cite this Research Publication : Gopal L. Khatik, Jasmine Kaur, Varun Kumar, Kulbhushan Tikoo and Vipin A. Nair "1,2,4-Oxadiazoles: a new class of anti-prostate cancer agents", Bioorganic and Medicinal Chemistry Letters 2012, 22, 1912-1916

Publisher : Elsevier

Year : 2012

Additive controlled, stereoselective benzylation of 2-thioxotetrahydropyrimidin-4(1H)-ones by chiral induction from a remote stereocentre

Cite this Research Publication : Varun Kumar, Anang Pal, Gopal L. Khatik, Suman Bhattacharya and Vipin A. Nair, "Additive controlled, stereoselective benzylation of 2-thioxotetrahydropyrimidin-4(1H)-ones by
chiral induction from a remote stereocentre", Tetrahedron: Asymmetry, 2012, 23, 434-442

Publisher : Elsevier

Year : 2012

Reversal of selectivity in acetate aldol reactions of N-acetyl-(S)-4-isopropyl-1-[(R)-1-phenylethyl] imidazolidin-2-one

Cite this Research Publication : Gopal L. Khatik, Varun Kumar and Vipin A. Nair, "Reversal of selectivity in acetate aldol reactions of N-acetyl-(S)-4-isopropyl-1-[(R)-1-phenylethyl] imidazolidin-2-one", Organic Letters, 2012, 14, 2442-2445

Publisher : American Chemical Society

Year : 2012

A facile synthesis and chemoselective reactions of dihydrothiouracils

Cite this Research Publication : Varun Kumar, Gopal L. Khatik, Anang Pal, Mohan R. Praneeth, Sanjay Bhattarai and Vipin A. Nair, "A facile synthesis and chemoselective reactions of dihydrothiouracils", Synlett 2012, 23, 2357-2362

Publisher : Thieme

Year : 2012

Stereoregulations of pyrimidinone based chiral auxiliary in aldol and alkylation reactions: a convenient route to oxyneolignans

Cite this Research Publication : Mangilal Chouhan, Ratnesh Sharma and Vipin A. Nair, "Stereoregulations of pyrimidinone based chiral auxiliary in aldol and alkylation reactions: a convenient route to oxyneolignans" Organic Letters, 2012, 14, 5672-5675

Publisher : American Chemical Society

Year : 2011

Enantiospecific synthesis of chiral 3-aryl-6-methyldihydrothiouracils from β-aminoesters

Cite this Research Publication : Vipin A. Nair "Enantiospecific synthesis of chiral 3-aryl-6-methyldihydrothiouracils from β-aminoesters", 11th International Congress for Young Chemists, October 12-16, 2011, Cracow, Poland

Year : 2011

Cp2ZrCl2-induced Reformatsky and Barbier reactions on isatins: an efficient synthesis of 3-substituted-3-hydroxyindolin-2-ones

Cite this Research Publication : Vipin A. Nair "Cp2ZrCl2-induced Reformatsky and Barbier reactions on isatins: an efficient synthesis of 3-substituted-3-hydroxyindolin-2-ones", International Conference on Green Chemistry, December 7-9, 2011, Central University of Rajasthan, Ajmer, Rajasthan, India.

Year : 2011

Reaction on water: a green approach for the synthesis of 3-substituted pyrrolidin-2,5-diones via Michael addition

Cite this Research Publication : Vipin A. Nair "Reaction on water: a green approach for the synthesis of 3-substituted pyrrolidin-2,5-diones via Michael addition", 3rd International Conference on Heterocyclic Chemistry, December 10-13, 2011, Jaipur, India.

Year : 2011

Reaction on water: a greener approach for the thia-Michael addition on N-aryl maleimides

Cite this Research Publication : Varun Kumar, Rangan Mitra, Sanjay Bhattarai and Vipin A. Nair, "Reaction on Water: A Greener Approach for the Thia Michael Addition on N-Aryl Maleimides", Synthetic Communications 2011, 41, 392-404

Publisher : Taylor & Francis

Year : 2011

Cp2ZrCl2-induced Reformatsky and Barbier reactions on isatins: an efficient synthesis of 3- substituted-3-hydroxyindolin-2-ones

Cite this Research Publication : Mangilal Chouhan, Ratnesh Sharma and Vipin A. Nair, "Cp2ZrCl2-induced Reformatsky and Barbier reactions on isatins: an efficient synthesis of 3-substituted-3-hydroxyindolin-2-ones", Applied Organometallic Chemistry, 2011, 25, 305-309.

Publisher : Wiley

Year : 2011

An efficient one-pot synthesis of 2-benzylpyrroles and 3-benzylindoles

Cite this Research Publication : Ratnesh Sharma, Mangilal Chouhan, Divya Sood and Vipin A. Nair,"An efficient one-pot synthesis of 2-benzylpyrroles and 3-benzylindoles", Applied Organometallic Chemistry 2011, 25, 470-475.

Year : 2011

Aldol derivatives of Thioxoimidazolidinones as potential anti-prostate cancer agents

Cite this Research Publication : Gopal L. Khatik, Jamine Kaur, Varun Kumar, Kulbushan Tikoo, Venugopalan P. and Vipin A. Nair, "Aldol derivatives of Thioxoimidazolidinones as potential anti-prostate cancer agents", European Journal of Medicinal Chemistry 2011, 46, 3291-3301

Publisher : Elsevier

Year : 2011

Highly efficient one-pot synthesis of 2-aminobenzoxazoles using triflic acid as a cyclodesulfurizing agent

Cite this Research Publication : Gopal L. Khatik, Namita Dube, Anang Pal and Vipin A. Nair, "Highly efficient one-pot synthesis of 2-aminobenzoxazoles using triflic acid as a cyclodesulfurizing
agent", Synthetic Communications, 2011, 41, 2631-2639

Year : 2011

Regiospecific epoxide opening: a facile approach for the synthesis of 3-hydroxy-3- aminomethylindolin-2-one derivatives

Cite this Research Publication : Mangilal Chouhan, Kishna Ram Senwar, Ratnesh Sharma, Vikas Grover and Vipin A. Nair, "Regiospecific epoxide opening: a facile approach for the synthesis of 3-hydroxy-3-
aminomethylindolin-2-one derivatives", Green Chemistry 2011, 13, 2553-2560

Publisher : Royal Society of Chemistry

Year : 2011

Asymmetric induction by (S)-4-isopropyl-1-phenylimidazolidin-2-thione in titanium mediated aldol reactions and its application in enantioselective synthesis of (R)-baclofen

Cite this Research Publication : Gopal L. Khatik, Ravi Khurana, Varun Kumar and Vipin A. Nair, "Asymmetric induction by (S)-4-isopropyl-1-phenylimidazolidin-2-thione in titanium mediated aldol
reactions and its application in enantioselective synthesis of (R)-baclofen", Synthesis, 2011, 43, 3123-3132

Publisher : Thieme

Year : 2011

Sterically controlled stereoregulations in aldol reactions of 3-aryl-1-alkyl dihydrothiouracils

Cite this Research Publication : Varun Kumar, Gopal L. Khatik and Vipin A. Nair, "Sterically controlled stereoregulations in aldol reactions of 3-aryl-1-alkyl dihydrothiouracils", Synlett, 2011, 22, 2997-3001.

Publisher : Thieme

Year : 2010

A highly efficient methodology for 5-methyl-3-aryl-2-thiooxazolidin-4-ones using lithium perchlorate in DIPEA mediated synthesis

Cite this Research Publication : Gopal L. Khatik, Anang Pal, Tushar D. Apsunde and Vipin A. Nair, "A highly efficient methodology for 5-methyl-3-aryl-2-thiooxazolidin-4-ones using lithium perchlorate in DIPEA mediated synthesis", Journal of Heterocyclic Chemistry 2010, 47, 734-739

Publisher : Wiley

Year : 2010

A facile approach to substituted acrylates by regioselective and stereoselective addition of thiols and amines to an alkynyl ester in water

Cite this Research Publication : Nitin A. Randive, Varun Kumar and Vipin A. Nair, "A facile approach to substituted acrylates by regioselective and stereoselective addition of thiols and amines to an alkynyl ester in water", Monatshefte für Chemie, 2010, 141, 1329-1332

Publisher : Springer

Year : 2010

Lithium perchlorate-induced electrophilic activation: one-pot synthesis of 3-aryl-2-thioxotetra hydropyrimidin-4-one derivatives from aryl isothiocyanates

Cite this Research Publication : Varun Kumar and Vipin A. Nair, "Lithium perchlorate-induced electrophilic activation: one-pot synthesis of 3-aryl-2-thioxotetra hydropyrimidin-4-one derivatives from aryl isothiocyanates", Tetrahedron Letters 2010, 51, 966-969.

Publisher : Elsevier

Year : 2010

A novel one-pot synthesis of 2-benzoylpyrroles from benzaldehydes

Cite this Research Publication : Ratnesh Sharma, Mangilal Chouhan and Vipin A. Nair, "A novel one-pot synthesis of 2-benzoylpyrroles from benzaldehydes", Tetrahedron Letters 2010, 51, 2039-2043

Publisher : Elsevier

Year : 2010

Stereochemical studies of 5-methyl-3-(substituted phenyl)-5-[(substituted phenyl) hydroxy methyl]-2-thiooxazolidin-4-ones

Cite this Research Publication : Gopal L. Khatik, Anang Pal, Shaikh M. Mobin and Vipin A. Nair, "Stereochemical studies of 5-methyl-3-(substituted phenyl)-5-[(substituted phenyl) hydroxy methyl]-2-thiooxazolidin-4-ones", Tetrahedron Letters 2010, 51, 3654-3657

Publisher : Elsevier

Year : 2010

Diastereoselective syntheses of 3-aryl-5-(4-arylalkyl)-6-methyl-1-(1-phenylethyl)thioxotetrahydro pyrimidin-4(1H)-ones: a stereochemical perspective from endo and exocyclic chiral centres

Cite this Research Publication : Varun Kumar, Pallepogu Raghavaiah, Shaikh M. Mobin and Vipin A. Nair, "Diastereoselective syntheses of 3-aryl-5-(4-arylalkyl)-6-methyl-1-(1-phenylethyl)thioxotetrahydro
pyrimidin-4(1H)-ones: a stereochemical perspective from endo and exocyclic chiral centres", Organic and Biomolecular Chemistry 2010, 8, 4960-4970

Year : 2006

Preclinical pharmacology of a nonsteroidal ligand for androgen receptor mediated imaging of prostate cancer

Cite this Research Publication : Jun Yang, Casey E. Bohl, Vipin A. Nair, Suni M. Mustafa, Duane D. Miller and James T. Dalton, "Preclinical pharmacology of a nonsteroidal ligand for androgen receptor mediated imaging of prostate cancer", Journal of Pharmacology and Experimental Therapeutics 2006, 317, 402-408

Publisher : American Society for Pharmacology and Experimental Therapeutics

Year : 2006

Synthesis of oxazolidinedione derived bicalutamide analogs

Cite this Research Publication : Vipin A. Nair, Suni M. Mustafa, Michael L. Mohler, James T. Dalton and Duane D. Miller, "", Tetrahedron Letters, 2006, 47, 3953-3955

Publisher : Elsevier

Year : 2005

Nonsteroidal tissue selective androgen receptor modulators: a promising class of clinical candidates

Cite this Research Publication : Michael L. Mohler, Vipin A. Nair, Dong Jin Hwang, Igor M. Rakov, Renukadevi Patil and Duane D. Miller, "Nonsteroidal tissue selective androgen receptor modulators: a promising class of clinical candidates", Expert Opinion on Therapeutic Patents 2005, 15, 1565-1585

Publisher : Informa

Year : 2005

Synthesis of irreversibly binding bicalutamide analogs for imaging studies

Cite this Research Publication : Vipin A. Nair, Suni M. Mustafa, Michael L. Mohler, Jun Yang, Leonid I. Kirkovsky, James T. Dalton and Duane D. Miller, "", Tetrahedron Letters 2005, 46, 4821-4823

Publisher : Elsevier

Year : 2004

Synthesis of 1, 2, 4-triazoles and thiazoles from thiosemicarbazide and its derivatives

Cite this Research Publication : Suni M. Mustafa, Vipin A. Nair, Joshua P. Chittoor and Sreekumar Krishnapillai, "Synthesis of 1, 2, 4-Triazoles and Thiazoles from Thiosemicarbazide and its Derivatives", Mini Reviews in Organic Chemistry 2004, 1, 375-385

Publisher : Bentham Science

Year : 2004

Synthesis of novel iodo derived bicalutamide analogs

Cite this Research Publication : Vipin A. Nair, Suni M. Mustafa, Michael L. Mohler, Scott J. Fisher, James T. Dalton and Duane D. Miller, "Synthesis of novel iodo derived bicalutamide analogs", Tetrahedron Letters 2004, 45, 9475-9477

Publisher : Elsevier

Year : 2004

Comparison of the pharmacological effects of a novel selective androgen receptor modulator (SARM), the 5α-reductase inhibitor finasteride, and the antiandrogen hydroxyflutamide in intact rats: new approach for benign prostate hyperplasia (BPH)

Cite this Research Publication : Wenqing Gao, Jeffrey D. Kearbey, Vipin A. Nair, Kiwon Chung, Parlow A. F., Duane D. Miller and James T. Dalton, "Comparison of the pharmacological effects of a novel selective androgen receptor modulator (SARM), the 5α-reductase inhibitor finasteride, and the antiandrogen hydroxyflutamide in intact rats: new approach for benign prostate hyperplasia (BPH)", Endocrinology 2004, 145, 5420-5428

Publisher : Oxford Academic

Year : 2003

Polystyrene supported β-diketone linked palladium complexes for olefin oxidation

Cite this Research Publication : Vipin A. Nair, M. M. Suni and K. Sreekumar, "Catalytic studies on polymer supported metal complexes", Designed Monomers and Polymers 2003, 6, 81-89

Publisher : Taylor & Francis

Year : 2003

Catalytic studies on polymer supported metal complexes

Cite this Research Publication : Vipin A. Nair, M. M. Suni and K. Sreekumar, "Polystyrene supported manganese complexes: heterogeneous catalysts for oxidation reactions", Journal of Polymer Research, 2003, 10, 267-273

Publisher : Springer

Year : 2003

Polystyrene Supported Manganese Complexes: Heterogeneous Catalysts for Oxidation Reactions

Cite this Research Publication : Vipin A. Nair, M. M. Suni and K. Sreekumar, "Polystyrene Supported Manganese Complexes: Heterogeneous Catalysts for Oxidation Reactions", Journal of Polymer Research, 2003, 10, 267-273

Publisher : Springer

Year : 2003

Heterogeneous catalysts for aromatic coupling and substitution reactions

Cite this Research Publication : Vipin A. Nair, M. M. Suni and K. Sreekumar, "Heterogeneous catalysts for aromatic coupling and substitution reactions", Reactive and Functional Polymers, 2003, 57, 33-40

Publisher : Elsevier

Year : 2002

Catalytic effects of poly(methyl methacrylate) supported β-diketone linked palladium complexes in olefin oxidation

Cite this Research Publication : Vipin A. Nair, M. M. Suni and K. Sreekumar, "Catalytic effects of poly(methyl methacrylate)-supportedβ-diketone-linked palladium complexes in olefin oxidation", Journal of Chemical Sciences, 2002, 114, 481-486

Publisher : Springer

Year : 2002

Poly(methyl methacrylate) supported β-diketone linked metal complexes: heterogeneous epoxidation catalysts

Cite this Research Publication : Vipin A. Nair and K. Sreekumar, "Poly(methyl methacrylate) supported β-diketone linked metal complexes: heterogeneous epoxidation catalysts", Journal of Polymer Materials, 2002, 19, 155-162

Publisher : Tech Science Press

Year : 2001

Heterocyclization of 1-alkyl-2-thiobiureas with α-haloketones

Cite this Research Publication : M. M. Suni, Vipin A. Nair and C. P. Joshua, "Heterocyclization of 1-alkyl-2-thiobiureas with α-haloketones", Tetrahedron Letters 2001, 42, 97-99

Publisher : Elsevier

Year : 2001

Heterocyclization of 1-aryl/alkyl-2-thiobiureas to 4-aryl/alkyl-3-substituted- Δ2-1,2,4-triazolin-5- ones

Cite this Research Publication : M. M. Suni, Vipin A. Nair and C. P. Joshua, "Heterocyclization of 1-aryl/alkyl-2-thiobiureas to 4-aryl/alkyl-3-substituted- Δ2-1,2,4-triazolin-5- ones", Tetrahedron, 2001, 57, 2003-2009

Publisher : Elsevier

Year : 2001

Synthesis of ureidothiazolines

Cite this Research Publication : M. M. Suni, Vipin A. Nair and C. P. Joshua, "Synthesis of ureidothiazolines", Synlett, 2001, 409-411

Publisher : Thieme

Year : 2001

Synthesis of substituted-Δ2-1,2,4-triazolin-5-ones and S-substituted isothiobiureas from 1-aryl/alkyl- 6-phenyl-2-thiobiureas

Cite this Research Publication : M. M. Suni, Vipin A. Nair and C. P. Joshua, "Synthesis of substituted-2-1,2,4-triazolin-5-ones and S-substituted isothiobiureas from 1-aryl/alkyl-6-phenyl-2-thiobiureas", Synthetic Communications, 2001, 31, 1599-1605

Publisher : Taylor & Francis

Year : 2001

Polymer supported catalysts for epoxidation reactions

Cite this Research Publication : Vipin A. Nair and K, Sreekumar, "Polymer supported catalysts for epoxidation reactions", Current Science 2001, 81, 194-197

Publisher : Indian Academy of Sciences

Conference Proceedings

Year : 2022

Perspectives in chiral auxiliary mediated aldol reactions, International Conference on Current Trends in Chemistry

Cite this Research Publication : Vipin A Nair "Perspectives in chiral auxiliary mediated aldol reactions, International Conference on Current Trends in Chemistry", March 11-12, 2022, Cochin University of Science and Technology, Cochin, India

Year : 2016

A highly efficient enantioselective synthesis of EEHP and EMHP: intermediates of PPAR agonists

Cite this Research Publication : Vipin A Nair, "A highly efficient enantioselective synthesis of EEHP and EMHP: intermediates of PPAR agonists", 19th CRSI National Symposium in Chemistry, July 14-16, 2016, Darjeeling, India.

Publisher : Elsevier

Year : 2012

Lithium perchlorate catalyzed synthesis of optically pure 3-aryl-6-methyl-1-(1-phenylethyl)- thioxotetrahydropyrimidin-4(1H)-ones and their absolute configuration determination by NMR

Cite this Research Publication : Vipin A Nair "Lithium perchlorate catalyzed synthesis of optically pure 3-aryl-6-methyl-1-(1-phenylethyl)-thioxotetrahydropyrimidin-4(1H)-ones and their absolute configuration determination by NMR", Indo US Workshop on Green Chemistry for Environment and Sustainable Development, March 11-13, 2012, Dehradun, India.

Year : 2011

Synthesis, stereochemical investigations and in vitro evaluation of anti (±)5-methyl-(3-substituted phenyl)-5-[(substituted phenyl)hydroxymethyl]-2-thixooxazolidin-4-ones on prostate cancer cell lines

Cite this Research Publication : Vipin A. Nair "Synthesis, stereochemical investigations and in vitro evaluation of anti (±)5-methyl-(3-substituted phenyl)-5-[(substituted phenyl)hydroxymethyl]-2-thixooxazolidin-4-ones on prostate cancer cell lines", Ramanbhai Foundation 5th International Symposium “Advances in Translational Research & Medicines”, February 1-4, 2011, Zydus Research Centre, Ahmedabad, India.

Year : 2011

A novel one-pot synthesis of 2-benzoylpyrroles from benzaldehydes

Cite this Research Publication : Vipin A. Nair "A novel one-pot synthesis of 2-benzoylpyrroles from benzaldehydes", Ramanbhai Foundation 5th International Symposium “Advances in Translational Research & Medicines” February 1-4, 2011, Zydus Research Centre, Ahmedabad, India.

Year : 2011

An efficient one-pot synthesis of 2-benzylpyrroles and 3-benzylindoles, International Conference on Green Chemistry (ICGC-2011)

Cite this Research Publication : Vipin A. Nair "An efficient one-pot synthesis of 2-benzylpyrroles and 3-benzylindoles", International Conference on Green Chemistry (ICGC-2011), December 7-9, 2011, Central University of Rajasthan, Ajmer, Rajasthan, India.

Year : 2010

Lithium perchlorate induced dual activation: one-pot synthesis of 3-aryl-2-thioxotetrahydropyrimidin- 4-one derivatives from aryl isothiocyanates

Cite this Research Publication : Vipin A. Nair "Lithium perchlorate induced dual activation: one-pot synthesis of 3-aryl-2-thioxotetrahydropyrimidin- 4-one derivatives from aryl isothiocyanates", International Conference on Practical Application of Modern Tools in Organic Synthesis, November 21-25, 2010, Indian Institute of Chemical Technology, Hyderabad, India.

Year : 2004

Synthesis and structure activity relationships of some non-steroidal selective androgen receptor modulators

Cite this Research Publication : Vipin A. Nair "Synthesis and structure activity relationships of some non-steroidal selective androgen receptor modulators", 228th American Chemical Society Meeting, August 22-26, 2004, Philadelphia, USA.

Experiences
Year Designation Institution
Jan 2024 to Till Date Associate Professor School of Biotechnology, Amrita Vishwa Vidyapeetham, Kollam, INDIA
June 2019 to Dec 2023 Associate Professor Department of Chemistry, REVA University, Bangalore, INDIA
Oct 2016 to Apr 2019 Senior Manager Chemistry Division, Anthem Biosciences, Bangalore, INDIA
Sep 2011 to Sep 2016 Associate Professor Department of Medicinal Chemistry, National Institute of Pharmaceutical Education and Research, Mohali, INDIA
Sep 2006 to Sep 2011 Assistant Professor Department of Medicinal Chemistry, National Institute of Pharmaceutical Education and Research, Mohali, INDIA
May 2006 to Sep 2006 Associate Scientific Manager Chemistry Division, Syngene (Biocon), Bangalore, INDIA
Aug 2001 to Mar 2006 Postdoctoral Research Department of Pharmaceutical Sciences, University of Tennessee, Memphis, USA
Jul 1998 to Jul 2001 Postdoctoral Research Doctoral Research, Department of Chemistry, University of Kerala, Trivandrum, India

Research Projects

Funded Research Projects

  • Investigations on Synergistic Effects of Novel Carbapenems as Antibacterial Agents and beta-Lactamase Inhibitors, 202J-2024, Council of Scientific & Industrial Research, Government of India
  • Selective Androgen Receptor Modulators, 2012-2015, Science & Engineering Research Board, Government of India
  • Target Specific New Drug Discovery Research ofAn t-tubercular Agents, 2007-2012, Ministry of Chemicals andFertilizers, Government of India
  • Functionalisation of Pyrrole by Dicylopentadienyl Zirconium Complex, 2007-2011,Council of Scientific & Industrial Research, Government ofindia
  • Second Generation Androgen Antagonists for Prostate Cancer, 2007-2010, Department of Science & Technology, Government of India
Teaching
  • Chemistry of Biomolecules
  • Advanced Phamaceutical Biotechnology
  • Biochemistry Practical
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