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Dr. Pavithran K.

Head of Department | Professor, Department of Medical Oncology and Hematology, School of Medicine, Kochi

Qualification: DM, MBBS, MD
pavithrank@aims.amrita.edu

Bio

Qualification: MD (Internal Medicine), DM (Medical Oncology), FRCP (London)

Dr. K. Pavithran currently serves as Professor and Head of the Department of Medical Oncology and Hematology at Amrita Institute of Medical Sciences. He took his MD in Internal Medicine from Calicut Medical College and DM in Medical Oncology from Kidwai Memorial Institute of Oncology, Bangalore. He is a Fellow of the Royal College of Physicians, London. He had his training in hematology from the Royal Hallamshire Hospital, Sheffield, United Kingdom and gained experience in bone-marrow transplantation from Fred Hutchinson Cancer Centre, Seattle, USA.

Dr. Pavithran is a member of many national (ISHTM, ISMPO, ISO, API, IMA, Indian Association of Cancer Research, ICON) and international organizations (American Society of Medical Oncology, European Society of Medical Oncology, International Medical Sciences Academy, International Association for the Study of Lung Cancer (IASLC).

He has presented many papers and delivered many lectures at various national and international conferences He has participated in more than 35 clinical trials.

He is also the reviewer for Biomed Central Journals (www.biomedcentral.com(link is external)), American Journal of Clinical Oncology, Supportive Oncology, Indian Journal of Cancer, Journal of Cancer Research and Experimental Oncology, Indian Journal of Medical & Pediatric Oncology, Journal of Association of Physicians of India, Indian Journal of Dermatology & Venereology, Indian Journal of Medical Sciences and Indian Journal of Hematology and Transfusion Medicine. He also serves in the editorial board of many national and international journals.

Publications

Journal Article

Year : 2024

SwinCNN: An Integrated Swin Transformer and CNN for Improved Breast Cancer Grade Classification

Cite this Research Publication : Sreelekshmi V,Pavithran K,Jyothisha J. Nair, SwinCNN: An Integrated Swin Transformer and CNN for Improved Breast Cancer Grade Classification, IEEE Access, 2024

Publisher : IEEE

Year : 2021

Triple intrathecal chemotherapy for leptomeningeal carcinomatosis in solid tumors: Treatment outcomes, response and their determinants

Cite this Research Publication : Srinivasalu VK, Subramaniam N, Philip A, Jose W, Pavithran K. "Triple intrathecal chemotherapy for leptomeningeal carcinomatosis in solid tumors: Treatment outcomes, response and their determinants," Indian Journal of Cancer, 2021 Jan-Mar;58(1):84-90. doi: 10.4103/ijc.IJC_730_18. PMID: 33402572.

Publisher : Indian Journal of Cancer

Year : 2021

Cancer nanomedicine developed from total human serum: a novel approach for making personalized nanomedicine.

Cite this Research Publication : Jyotsna Thayath, Dr. Pavithran K., Shantikumar V Nair, and Dr. Manzoor K., “Cancer nanomedicine developed from total human serum: a novel approach for making personalized nanomedicine.”, Nanomedicine, vol. 16, no. 12, pp. 997-1015, 2021.

Publisher : Nanomedicine (Lond)

Year : 2021

Malignant Gastrointestinal Neuroectodermal Tumour-Case Report with Review of Literature.

Cite this Research Publication : A. Damle, Sreenija, Y., Mathews, N. Rebecca, Nair, K., Philp, A., Dr. Pavithran K., and Paulose, R. Rachel, “Malignant Gastrointestinal Neuroectodermal Tumour-Case Report with Review of Literature.”, J Gastrointest Cancer, 2021.

Publisher : J Gastrointest Cancer

Year : 2021

Ripretinib: A narrative drug review

Cite this Research Publication : S. S. Kumar, Arun Philip, and Dr. Pavithran K., “Ripretinib: A narrative drug review”, Cancer Research, Statistics, and Treatment , vol. 4, no. 1, pp. 93-98, 2021.

Publisher : Cancer Research, Statistics, and Treatment

Year : 2021

Diagnostic utility of medical thoracoscopy in T cell lymphoblastic lymphoma presenting with pleural effusion.

Cite this Research Publication : A. A. Mehta, Shafi, T. M., Nambiar, A., and Dr. Pavithran K., “Diagnostic utility of medical thoracoscopy in T cell lymphoblastic lymphoma presenting with pleural effusion”, Respiratory Medicine Case Reports, vol. 32, p. 101322, 2021, DOI: 10.1016/j.rmcr.2020.101322

Publisher : Respiratory Medicine Case Reports

Year : 2021

Long-term survival outcome of advanced epithelial ovarian cancer: A single institutional study.

Cite this Research Publication : P. Viral, Rajanbabu, A., Dr. Pavithran K., Chithrathara, K., Nair, I. R., Bhaskaran, R., Gangadharan, P., and Vijaykumar, D. K., “Long-term survival outcome of advanced epithelial ovarian cancer: A single institutional study.”, Indian J Cancer, 2021.

Publisher : Indian J Cancer

Year : 2021

Metastatic endometrial carcinoma responsive to pembrolizumab

Cite this Research Publication : G. Gandham​, Jayamohanan, H., Anupama Rajanbabu, and Dr. Pavithran K., “Metastatic endometrial carcinoma responsive to pembrolizumab”, International Journal of Molecular & Immuno Oncology , vol. 6, no. 1, pp. 50-53, 2021.

Publisher : International Journal of Molecular & Immuno Oncology

Year : 2021

Tazemetostat– A Drug review

Cite this Research Publication : A. K. Paul, Jayamohanan, H., and Dr. Pavithran K., “Tazemetostat– A Drug review”, International Journal of Research in Pharmaceutical Sciences, vol. 12, no. 1, pp. 894-898, 2021.

Publisher : International Journal of Research in Pharmaceutical Sciences

Year : 2021

Ten-year survival outcome of breast cancer patients in India

Cite this Research Publication : P. Viral, Dr. Pavithran K., Beena, K., Shaji, A., and Vijaykumar, D., “Ten-year survival outcome of breast cancer patients in India”, Journal of Carcinogenesis, vol. 20, no. 1, pp. 1 - 1, 2021.

Publisher : Journal of Carcinogenesis

Year : 2020

Imatinib-induced Haematuria Necessitating Drug Discontinuation

Cite this Research Publication : A. Hemakumar and Dr. Pavithran K., “Imatinib-induced Haematuria Necessitating Drug Discontinuation”, Journal of Onco-Nephrology, pp. 1-3, 2020.

Publisher : Journal of Onco-Nephrology

Year : 2020

Isolated Splenic Metastasis from Ovarian Carcinoma

Cite this Research Publication : Dr. Pavithran K., ,, F, N., and A, R., “Isolated Splenic Metastasis from Ovarian Carcinoma”, Indian J Gynecol Oncolog 2020, vol. 18, 2020.

Publisher : Indian J Gynecol Oncolog

Year : 2020

Primary Neuroendocrine Carcinoma of the Larynx: A Case Report

Cite this Research Publication : Dr. Pavithran K., GR, D., H, J., NV, S., R, A., A, N., and T, K., “Primary Neuroendocrine Carcinoma of the Larynx: A Case Report”, Indian Journal of Otolaryngology and Head & Neck Surgery, 2020.


Publisher : Indian Journal of Otolaryngology and Head & Neck Surgery

Year : 2020

Primary Tumor Location as a Prognostic and Predictive Marker in Metastatic Colorectal Cancer (mCRC)

Cite this Research Publication : Bahl A, Talwar V, Sirohi B, Mehta P, Arya D, Shrivastava G, Dahiya A and Pavithran K, "Primary Tumor Location as a Prognostic and Predictive Marker in Metastatic Colorectal Cancer (mCRC)," Frontiers in Oncology, 10:964. doi: 10.3389/fonc.2020.00964. (2020)

Publisher : Frontiers in Oncology

Year : 2020

Pemetrexed-Associated Hyperpigemented Skin Rash

Cite this Research Publication : Dr. Pavithran K., E, D., R, K., L, R., S, R., and A, P., “Pemetrexed-Associated Hyperpigemented Skin Rash”, Am J Ther 2020 , 2020.

Publisher : Am J Ther

Year : 2020

Immunohistochemical Markers of Tumor Microenvironment as Prognostic Predictors in Diffuse Large B-Cell Lymphoma: Study from an Oncology Centre in South India

Cite this Research Publication : Dr. Pavithran K., RN, I., S, A., and P, P., “Immunohistochemical Markers of Tumor Microenvironment as Prognostic Predictors in Diffuse Large B-Cell Lymphoma: Study from an Oncology Centre in South India”, Asian J Oncology, 2020.

Publisher : Asian J Oncology

Year : 2020

Impact of St. Gallen Surrogate Classification for Intrinsic Breast Cancer Sub-types on Disease Features, Recurrence, and Survival in South Indian Patients

Cite this Research Publication : Dr. Pavithran K., B, K., RV, R., and DK, V., “Impact of St. Gallen Surrogate Classification for Intrinsic Breast Cancer Sub-types on Disease Features, Recurrence, and Survival in South Indian Patients”, Indian J Cancer, vol. 57, no. 1, pp. 49-54, 2020.

Publisher : Indian J Cancer

Year : 2020

Therapeutic Drug Monitoring of Sorafenib in Hepatocellular Carcinoma Patients

Cite this Research Publication :
T. Sachu, Aneesh, P., Dr. Umadevi P., and Dr. Pavithran K., “Therapeutic Drug Monitoring of Sorafenib in Hepatocellular Carcinoma Patients”, Therapeutic drug monitoring, vol. 42, no. 2, pp. 345-347, 2020.

Publisher : Therapeutic drug monitoring

Year : 2019

Clinical Evidence of Regorifenib in Metastatic Colorectal Cancer: A Case Report

Cite this Research Publication : S. K. Mathew, Thomas, A., R, R. P., Sivadas, A., and Dr. Pavithran K., “Clinical Evidence of Regorifenib in Metastatic Colorectal Cancer: A Case Report”, Research Journal of Pharmacy and Technology, vol. 12, no. 2, 2019.

Publisher : Research Journal of Pharmacy and Technology,

Year : 2019

A comparative study on erlotinib & gefitinib therapy in non-small cell lung carcinoma patients

Cite this Research Publication : P. Thomas, Vincent, B., George, C., Joshua, J. Mariam, Dr. Pavithran K., and Meenu Vijayan, “A comparative study on erlotinib & gefitinib therapy in non-small cell lung carcinoma patients”, Indian J Med Res, vol. 150, no. 1, pp. 67-72, 2019.

Publisher : Indian J Med Res

Year : 2019

Effectiveness of zolpidem and sleep hygiene counseling in the treatment of insomnia in solid tumor patients.

Cite this Research Publication : A. Asok, Sreekumar, S., Radhika,, Cc, A., Dr. Umadevi P., and Dr. Pavithran K., “Effectiveness of zolpidem and sleep hygiene counseling in the treatment of insomnia in solid tumor patients.”, J Oncol Pharm Pract, vol. 25, no. 7, pp. 1608-1612, 2019.

Publisher : J Oncol Pharm Pract

Year : 2017

Short-course lenalidomide plus low-dose dexamethasone in the treatment of newly diagnosed multiple myeloma— A single-centre pragmatic study

Cite this Research Publication : W. M. Jose, Pavithran, K., and Ganesan, T. S., “Short-course lenalidomide plus low-dose dexamethasone in the treatment of newly diagnosed multiple myeloma— A single-centre pragmatic study”, Current Oncology, vol. 24, pp. e361-e367, 2017.

Publisher : Current Oncology

Year : 2017

Bence Jones Myeloma- An Analysis of 28 Cases

Cite this Research Publication : D. Abdul Maje K and K, D. Pavithran, “Bence Jones Myeloma- An Analysis of 28 Cases ”, IJSR - INTERNATIONAL JOURNAL OF SCIENTIFIC RESEARCH, 2017.

Publisher : IJSR - INTERNATIONAL JOURNAL OF SCIENTIFIC RESEARCH

Year : 2016

Neoadjuvant Chemotherapy Followed by Neoadjuvant Concurrent Chemoradiation for Locally Advanced Breast Cancer: a Feasibility Study and 10-year Follow-up Results

Cite this Research Publication : Beena Kunheri, Kottarathil, V. Dehannathp, Makuny, D., Keechilat, P., and Padmanabhan, T. K., “Neoadjuvant Chemotherapy Followed by Neoadjuvant Concurrent Chemoradiation for Locally Advanced Breast Cancer: a Feasibility Study and 10-year Follow-up Results”, Indian Journal of Gynecologic Oncology, vol. 14, p. 60, 2016.

Publisher : Indian Journal of Gynecologic Oncology.

Year : 2016

Carcinoma esophagus. Practical Gastroenterology

Cite this Research Publication : P. K, “Carcinoma esophagus. Practical Gastroenterology”, 2016.

Publisher : (2016).

Year : 2013

The role of Gefitinib in patients with non-small-cell lung cancer in India

Cite this Research Publication : A. Aa Mehta, Jose, W. Mb, Pavithran, Kb, and Triavadi, G. Sc, “The role of Gefitinib in patients with non-small-cell lung cancer in India”, Indian Journal of Palliative Care, vol. 19, pp. 48-53, 2013.

Publisher : Indian Journal of Palliative Care

Year : 2013

Report of a Case of Radiation-Induced New-Onset Vitiligo with collective review of cases in the Literature of Radiation-Related Vitiligo

Cite this Research Publication : K. Pavithran, Pande, S. Brahmanand, and Dinesh, M., “Report of a Case of Radiation-Induced New-Onset Vitiligo with collective review of cases in the Literature of Radiation-Related Vitiligo”, Case reports in medicine, vol. 2013, 2013.

Publisher : Case reports in medicine

Year : 2013

Recent Advances in Granulosa Cell Tumor Ovary: A Review

Cite this Research Publication : V. Dab Kottarathil, Antony, M. Ac, Nair, I. Rd, and Pavithran, Ke, “Recent Advances in Granulosa Cell Tumor Ovary: A Review”, Indian Journal of Surgical Oncology, vol. 4, pp. 37-47, 2013.

Publisher : Indian Journal of Surgical Oncology

Year : 2012

Janus kinase inhibitors: Jackpot or potluck?

Cite this Research Publication : K. Pavithran and Pande, S. B., “Janus kinase inhibitors: Jackpot or potluck?”, Oncology Reviews, vol. 6, pp. 101-108, 2012.

Publisher : Oncology Reviews

Year : 2012

Bilateral adenoid cystic carcinoma of the breast: Report of a rare case with a rare presentation

Cite this Research Publication : M. Palaniappan, Athira, U., ,, Pavithran, K., and Jojo, A., “Bilateral adenoid cystic carcinoma of the breast: Report of a rare case with a rare presentation”, Journal of Clinical and Diagnostic Research, vol. 5, pp. 1440-1443, 2012.

Publisher : Journal of Clinical and Diagnostic Research

Year : 2011

Standards Practice and Safe Handling of Chemotherapy Drugs

Cite this Research Publication : Chitra P., M., D. Jeyagowri, and Dr. Pavithran K., “Standards Practice and Safe Handling of Chemotherapy Drugs”, Prisms Nursing Practice, vol. 6, no. 3, 2011.

Publisher : Prisms Nursing Practice

Year : 2010

Multiple myeloma presenting as eosinophilic pleural effusion

Cite this Research Publication : A. Aa Mehta, Venkatakrishnan, Ra, Jose, Wb, Palaniappan, Mb, and Pavithran, Kb, “Multiple myeloma presenting as eosinophilic pleural effusion”, Asia-Pacific Journal of Clinical Oncology, vol. 6, pp. 256-259, 2010.

Publisher : Asia-Pacific Journal of Clinical Oncology

Year : 2010

Foot Massage – A Nursing Practice

Cite this Research Publication : Chitra P., M., D. Jeyagowri, and Dr. Pavithran K., “Foot Massage - A Nursing Practice”, Prisms Nursing Practice, vol. 5, no. 1, 2010.



Publisher : Prisms Nursing Practice

Year : 2010

Autoimmune thrombocytopenic purpura in acute hepatitis A-A report and review of literature

Cite this Research Publication : W. Jose, Kumar, K., Unnikrishnan, A., Palaniappan, M., Nair, A., and Pavithran, K., “Autoimmune thrombocytopenic purpura in acute hepatitis A-A report and review of literature”, Asia-Pacific Journal of Oncology and Hematology, vol. 2, pp. 137-139, 2010.

Publisher : Asia-Pacific Journal of Oncology and Hematology

Year : 2008

Nursing Intervention in Laughter Therapy

Cite this Research Publication : Chitra P., M., D. Jeyagowri, and Dr. Pavithran K., “Nursing Intervention in Laughter Therapy”, Nightingale Nursing Times, vol. 4, no. 8, 2008.

Publisher : Nightingale Nursing Times

Year : 2008

Complementary medicine and alternative therapies

Cite this Research Publication : Chitra P., M., D. Jeyagowri, and Dr. Pavithran K., “Complementary medicine and alternative therapies”, Indian Journal of Holistic Nursing, vol. 4, no. 2, 2008.


Publisher : Indian Journal of Holistic Nursing

Achievements

He has been awarded Fellowship by the World Federation of Haemophilia in 1993 and Indian College of Physicians in 2003. He is also a Fellow of International Medical Sciences Academy and a Fellow of the Royal College of Physicians, London.

He has to his credit numerous publications (80 papers in International Journals and 98 in National Journals). He has edited two books on cancer (Essentials of Clinical Oncology and A Companion to Essentials of Clinical Oncology) and has contributed more than 40 chapters in various books

Clinical Trials – Ongoing
  • A Phase II Randomized, Multi-Center, Double-Blind, Global Study to Determine the Efficacy and Safety of Durvalumab plus Olaparib Combination Therapy Compared with Durvalumab Monotherapy as Maintenance Therapy in Patients whose Disease has not Progressed Following Standard of Care Platinum-Based Chemotherapy with Durvalumab in First-Line Stage IV Non-Small Cell Lung Cancer (ORION)
  • A global, multicenter, three arms, open-label randomized study to evaluate the efficacy and safety of Nanosomal Docetaxel Lipid Suspension compared to Taxotere® (Docetaxel Injection Concentrate) in triple-negative breast cancer patients with locally advanced or metastatic breast cancer after failure to prior chemotherapy
  • A Prospective, Randomized, Multicentre, Comparative, open-label, Parallel study to evaluate the Efficacy, Safety and Pharmacokinetics of Test-Trastuzumab Emtansine (ZRC-3256; Cadila Healthcare Ltd) and Reference-Trastuzumab Emtansine (Kadcyla®, a product of Roche) in HER2- Positive Metastatic Breast Cancer Patients.
  • Reditux™ Registry to Compare Effectiveness, Safety, and Resource Utilization of Reditux™ v-s. the Reference Medicinal Product to Treat Diffuse Large B-Cell Lymphoma and Chronic Lymphocytic Leukaemia in Routine Clinical Practice.
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