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Dr. Jayakumar Rangasamy

Professor, Amrita School of Nanosciences and Molecular Medicine, Kochi

Qualification: Ph.D
rjayakumar@aims.amrita.edu

Bio

Dr. R. Jayakumar is a Professor at the Polymeric Biomaterials group, Centre for Nanosciences and Molecular Medicine (ACNSMM), Amrita Vishwa Vidyapeetham, specializing in the area of Biomaterials for Healthcare Applications. Dr. R. Jayakumar joined ACNSMM in November 2007. He received his Ph.D. in Polymer Chemistry from Anna University, Chennai, India (2002). Dr. Jayakumar’s research laboratory at ACNSMM focuses on development of biodegradable polymeric nanofibers, nanogels, nanoparticles, nanocomposite scaffolds and injectable hydrogels for Tissue Engineering, Drug Delivery, and Wound Dressing applications.

Dr. Jayakumar’s academic achievements include third rank in M. Sc. from Bharathidasan University, Senior Research Fellowship from the Council of Scientific and Industrial Research (CSIR), Govt. of India (2001), University Postdoctoral Fellowship from Chonbuk National University (2002-2003), South Korea, and FCT Postdoctoral Fellowship from the Government of Portugal (2003-2005). Dr. Jayakumar was also awarded the prestigious JSPS Postdoctoral Fellowship (2005-2007) from the Japan Society for the Promotion of Science (JSPS), Japan. Dr. Jayakumar has over 240 Journal publications, 4 books, 12 book chapters, and 10 filed patents to his credit. His publications have been cited more than 14100 times with h-index-62. Dr. Jayakumar is also the recipient of several other awards like Best Paper Award from Journal of Materials Science Materials in Medicine (Springer) and IET Nanobiotechnology Journal, Faculty Researcher Award – 2016 from Indian Chitin and Chitosan Society (ICCS), India,the very prestigious MRSI Medal-2017 from Materials Research Society of India (MRSI, and the India Research Excellence-Citation Awards-2017 (Health & Medical Science area) from Clarivate Analytics, Web of Science. Dr. Jayakumar is a reviewer and editorial board member of many international journals. Dr. Jayakumar has completed more than 17 funded projects and is currently involved with 4 ongoing projects. He has active collaborations with many research groups in USA, Japan, South Korea, Portugal, and Taiwan.

Research

The Lab key focus is on understanding and designing biomaterials using biomimetic approach for tissue regeneration. Our research interests are development of injectable hydrogels, electrospun scaffolds and scaffolds for wound healing.

Injectable Hydrogels

The desire and need to minimize traditional open surgeries is gearing up as it could reduce the healthcare expenses and improve the recovery time for the patients. Injectable hydrogels with their ease of handling, complete filling of the defect area and good permeability have emerged as promising biomaterials. The Jayakumar group designs shear thinning injectable hydrogel and in situ cross-linked hydrogel with bio-inspired polymers and nanoparticles for tissue regeneration. Injectable hydrogels are designed for effective regeneration of functional tissue, such as bone, fat, and cartilage. Further, work is also been directed towards achieving therapeutic angiogenesis in order to revascularize ischemic tissues and in developing cost effective injectable hydrogel and bioadhesive hydrogel for haemostatic applications. Bioadhesive hydrogel loaded with antibacterial drug is being developed for treating mediastinitis.

Electrospun Scaffolds

Electrospun fibres’ possess unique properties promise to make key bioengineered material for tissue regeneration. We fabricate fibres in different 3-D forms so as to make layered tubular constructs, thick layered fibrous scaffolds, braided and rolled fibre scaffolds. The Jayakumar group is developing approaches to control cell differentiation through surface modification of electrospun fibres. Further, work is also directed towards designing scaffolds for tendon and ligament regeneration using electrospun fibre scaffold.

Wound Healing

Natural process of wound healing is impaired in many pathological conditions, resulting in chronic wounds. Pathological conditions arising as of diabetic conditions, hyperfibrinolytic conditions, polymicrobial infection, burn wounds etc are create different complications in the treatment for wound healing. The underlying pathology in these conditions is not fully understood. The Jayakumar group in developing bandages in addressing in the problems in the above mentioned situations

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Publications
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