Publication

Abstract : Regenerative medicine focuses on repair/replacement of the damaged tissue or organ in our body. This is done by growing cells on scaffold materials which help in its attachment, migration and proliferation. Chitosan being natural polymer has many unique properties such as being biocompatible, biodegradable and also has antibacterial and wound-healing abilities. Gelatin a derivative of collagen, which is widely present in our body, has been used as a composite with chitosan for promoting cell attachment, proliferation, and differentiation. Composite scaffolds have also shown better mechanical and functional properties because these composites are made of polymer and inorganic/organic blenders. Overall this review focuses on the role of chitosan-gelatin-based composite scaffolds in bone tissue engineering.