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Bioactive and metal uptake studies of carboxymethyl chitosan-graft-d-glucuronic acid membranes for tissue engineering and environmental applications

Publication Type : Journal Article

Thematic Areas : Nanosciences and Molecular Medicine

Publisher : International Journal of Biological Macromolecules

Source : International Journal of Biological Macromolecules, Volume 45, Number 2, p.135 - 139 (2009)

Url : http://www.sciencedirect.com/science/article/pii/S0141813009000853

Keywords : Bioactivity, chitosan, Grafting, Metal uptake studies, XRD studies

Campus : Kochi

School : Center for Nanosciences

Center : Amrita Center for Nanosciences and Molecular Medicine Move, Nanosciences

Department : Nanosciences and Molecular Medicine

Year : 2009

Abstract : Carboxymethyl chitosan-graft-d-glucuronic acid (CMCS-g-d-GA) was prepared by grafting d-GA onto CMCS in the presence of 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide (EDC) and then the membranes were made from it. In this work, the bioactivity studies of CMCS-g-d-GA membranes were carried out and then characterized by SEM, CLSM, XRD and FT-IR. The CMCS-g-d-GA membranes were found to be bioactive. The adsorption of Ni2+, Zn2+and Cu2+ ions onto CMCS-g-d-GA membranes has also been investigated. The maximum adsorption capacity of CMCS-g-d-GA for Ni2+, Zn2+and Cu2+ was found to be 57, 56.4 and 70.2mg/g, respectively. Hence, these membranes were useful for tissue engineering, environmental and water purification applications.

Cite this Research Publication : Dr. Jayakumar Rangasamy, Rajkumar, M., Freitas, H., Kumar, P. T. Sudheesh, Nair, S. V., Furuike, T., and Tamura, H., “Bioactive and metal uptake studies of carboxymethyl chitosan-graft-d-glucuronic acid membranes for tissue engineering and environmental applications”, International Journal of Biological Macromolecules, vol. 45, pp. 135 - 139, 2009.

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