Publication Type : Journal Article
Thematic Areas : Medical Sciences
Publisher : Indian Journal of Clinical Biochemistry
Source : Indian Journal of Clinical Biochemistry, Volume 24, Number 2, p.155-158 (2009)
Url : http://www.scopus.com/inward/record.url?eid=2-s2.0-74049111929&partnerID=40&md5=8d90598ef6e4253ad568e9ca937df957
Keywords : adult, alanine aminotransferase, article, aspartate aminotransferase, bilirubin, bilirubin blood level, diabetes mellitus, Fatty Liver, female, human, hyperlipidemia, India, major clinical study, male, non alcoholic fatty liver disease, obesity
Campus : Kochi
School : School of Medicine
Department : Biochemistry
Year : 2009
Abstract : Non-alcoholic fatty liver disease and its more aggressive form, non-alcoholic steatohepatitis are entities that are becoming more and more interesting to the medical community in general. A total of 93 Non-alcoholic fatty liver disease patients (64 male and 29 female) within the age range between 28 to 63 years were studied. All of them showed elevated alanine aminotransferase level (104.07 ± 56.04). Aspartate aminotransferase level (58.13 ± 31.96) was elevated more than its normal level in 82% cases and AST to ALT ratio was found 0.59 ± 0.26. Predisposing factors were diabetes mellitus (37%), obesity (13%) and hyperlipidemia (41%). In addition, 32% of the subjects were overweight.18% of the patients had elevated serum bilirubin. Our findings recommend a lower cutoff value than suggested by the World Health Organization for overweight and obesity among this racial-ethnic group. © 2009 Association of Clinical Biochemists of India.
Cite this Research Publication : D. M. Vasudevan, Das, S. K., Mukherjee, S., Pandey, G., and Balakrishnan, V., “Clinicopathological spectrum of non-alcoholic fatty liver disease among patients in Kerala”, Indian Journal of Clinical Biochemistry, vol. 24, pp. 155-158, 2009.