Purpose: This paper aims to explore the importance of three information technology (IT) capabilities, namely, outside-in, spanning and inside-out in the development of tourism supply chain (TSC) agility and resilience. Furthermore, the study also explored the moderating role of technology orientation (TO) on the proposed linkages. Design/methodology/approach: The study adopted a multi-unit study of TSC. Consequently, perceptual data were gathered from two prominent entities in a typical TSC, namely, hotel managers and travel and tour operators. The responses were gathered using an email survey and were analysed using partial least squares in SmartPLS 2.0.M3. Findings: Based on 221 completed responses, our study showed outside-in IT capability as an essential enabler for tourism agility and resilience. While spanning IT capability did not have any significant influence on tourism agility; it is a prominent enabler for tourism resilience. Inside-out IT capability did not have any significant influence on tourism resilience; however, it is a prominent enabler of tourism agility. Furthermore, TO was found as a positive moderator in outside-in IT capability? tourism agility; outside-in IT capability? tourism resilience linkages. Furthermore, it also acted as a positive moderator in spanning IT capability? tourism resilience linkage and inside-out IT capability? tourism agility linkage. Originality/value: The study is the foremost to explore the importance of IT capabilities in the development of dynamic capabilities of agility and resilience in tourism. Furthermore, the study also is the foremost to explore the contingent role of TO in enhancing the influence of IT capabilities in tourism agility and resilience. © 2019, Emerald Publishing Limited.