Isolated intracranial Rosai Dorfman disease
Publication Type:Journal Article
Source:Neurology India, Volume 59, Number 3, p.443-446 (2011)
Keywords:adult, Anti-Inflammatory Agents, article, case report, Central Nervous System Diseases, computer assisted tomography, craniotomy, Dura Mater, Gait Disorders, hemiparesis, Histiocytes, Histiocytosis, histopathology, human, human tissue, Humans, immunohistochemistry, low drug dose, Magnetic Resonance Imaging, male, meningioma, middle aged, Neurologic, neurologic examination, nuclear magnetic resonance imaging, Rosai Dorfman disease, Sinus, steroid
Rosai Dorfman disease (RDD), also known as sinus histiocytosis with massive lymphadenopathy, is a benign histiocytic proliferative disorder mainly affecting the lymph nodes. Although several cases of extra-nodal involvement have been reported previously, central nervous system involvement, particularly in the absence of nodal disease is extremely rare. We report a case of isolated intracranial RDD occurring in a relatively elder patient, which was shown by histological examination to have a dura-based involvement.
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