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Small-colony variant selection as a survival strategy for Staphylococcus aureus in the presence of Pseudomonas aeruginosa

Publication Type : Journal Article

Thematic Areas : Nanosciences and Molecular Medicine

Publisher : Applied and environmental microbiology

Source : Applied and environmental microbiology, Am Soc Microbiol, Volume 75, Number 21, p.6910–6912 (2009)

Url : http://aem.asm.org/content/75/21/6910.short

Campus : Kochi

School : Center for Nanosciences

Center : Amrita Center for Nanosciences and Molecular Medicine Move, Nanosciences

Department : Nanosciences and Molecular Medicine

Year : 2009

Abstract : Previously it has been demonstrated that Staphylococcus aureus is sensitive toward Pseudomonas-secreted exotoxins, which preferentially target the electron transport chain in staphylococci. Here it is shown that a subpopulation of S. aureus survives these respiratory toxins of Pseudomonas aeruginosa by selection of the small-colony variant (SCV) phenotype. Purified pyocyanin alone causes the same effect. A hemB mutant of S. aureus survives cocultivation with P. aeruginosa without a decrease in CFU.

Cite this Research Publication : L. Biswas, Dr. Raja Biswas, Schlag, M., Bertram, R., and Götz, F., “Small-colony variant selection as a survival strategy for Staphylococcus aureus in the presence of Pseudomonas aeruginosa”, Applied and environmental microbiology, vol. 75, pp. 6910–6912, 2009.

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