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Publication Type : Patents
Thematic Areas : Nanosciences and Molecular Medicine
Publisher : US Patent 10,893,931
Source : Volume US Patent 10,893,931 (2021)
Campus : Kochi
School : Center for Nanosciences
Center : Amrita Center for Nanosciences and Molecular Medicine Move, Nanosciences
Year : 2021
Abstract : An apparatus for fabrication of a woven tubular nanotextile used in vascular graft applications. The woven nanotextile conduit is 0.1 to 50 mm in diameter and includes a multitude of hierarchically arranged nanofibers. They are made from low strength bundled nanoyarns containing thousands of nanofibers with improved mechanical strength. The weaving apparatus interweaves the warp and weft yarns in longitudinal and transverse directions, resulting in a flexible and strong woven product. The physical and biological properties of the woven nanotextile were significantly enhanced when compared to non-woven nanofibrous form and conventional medical textiles. The nanotextile displayed superhydrophilic behavior in an otherwise hydrophobic material and when implanted as a vascular graft was robust, suturable, kink-proof and non-thrombogenic, with complete endothelialization of the graft luminal area.
Cite this Research Publication : D. Menon, Joseph, J., Varma, P., and Nair, S., “Strong, flexible, and thrombus-free woven nanotextile based vascular grafts, and method of production thereof”, 2021.