Publication Type : Journal Article
Thematic Areas : Medical Sciences
Publisher : Radiobiologia Radiotherapia
Source : Radiobiologia Radiotherapia (1984)
Campus : Kochi
School : School of Medicine
Department : Biochemistry
Year : 1984
Abstract : The effect of anti-radiation compound MPG (2-mercaptopropionyl glycine) on the peripheral blood has been studied in Swiss albino mice irradiated (1 and 3 Gy) at the age of two weeks. It was observed that 1.0 Gy did not produce any noticeable changes in the erythrocyte count and hemoglobin level in both drug-treated and non-drug-treated groups. Whereas after 3.0 Gy exposure a significant depletion in both the parameters was noticed on 3 and 4 weeks old animals. As compared to normal total leukocyte and lymphocyte counts were depleted significantly in two weeks old animals in both the exposure groups. MPG alone did not produce any noticeable changes in different blood parameters of two weeks old animals after 6 hours exposure. After one week exposure MPG caused significant elevation in different blood components of three weeks old animals and compared with control it caused earlier and faster recovery.
Cite this Research Publication : S. Kumar, Joseph, C. D., Vasudevan, D. M., and P Devi, U., “Radiation-induced peripheral blood changes in mice and its modification by MPG”, Radiobiologia Radiotherapia, 1984.