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Dr. Aswathy Alangode

Assistant professor, School of Biotechnology, Amritapuri | Research Scholar, Venomics Labs, School of Biotechnology, Amritapuri

Qualification: BSc, MSc
aswathya@am.amrita.edu
Research Interest: Natural product Lead Discovery, Venomics

Bio Publications Awards and Honors Research Projects Education Teachings
Bio

Dr. Aswathy Alangode currently serves as an Assistant Professor at the School of Biotechnology, Amrita Vishwa Vidyapeetham, Amritapuri. She holds a Ph.D in Biotechnology from Amrita Vishwa Vidyapeetham. Her research was focused on unravelling the molecular mechanisms underlying the enhancement of fibrinogenolysis by venom proteases in the presence of different compounds and to analyse the physiological role of these compounds in mediating envenomation by Russell’s viper venom. Her research interest includes purification and characterization of snake venom components as well as therapeutic applications of snake venom

Publications

Journal Article

Year : 2020

Sodium oleate, arachidonate, and linoleate enhance fibrinogenolysis by Russell’s viper venom proteinases and inhibit FXIIIa; a role for phospholipase A2 in venom induced consumption coagulopathy.

Cite this Research Publication : Aswathy Alangode, Margaret Reick, Martin Reick,Sodium oleate, arachidonate, and linoleate enhance fibrinogenolysis by Russell's viper venom proteinases and inhibit FXIIIa; a role for phospholipase A2 in venom induced consumption coagulopathy. Toxicon,2020

Publisher : Toxicon

Year : 2020

Snake antivenom: Challenges and alternate approaches

Cite this Research Publication : A. Alangode, Karthika Rajan, and Dr. Bipin G. Nair, “Snake antivenom: Challenges and alternate approaches”, Biochemical Pharmacology, vol. 181, p. 114135, 2020.

Publisher : Biochemical Pharmacology

Conference Proceedings

Year : 2017

Proteomic investigation of Trimeresurus malabaricus venom and its comparative functional analysis using Daboia Russelii venom, SnakeSymp-Snake venom research and snakebite therapy

Cite this Research Publication : Muralidharan Vanuopadath, Aswathy Alangode, Karthika Rajan, Nithin Sajeev, Dileepkumar Raveendran, Martein Reick, Margaret Reick, Bipin Gopalakrishnan Nair, Sudarslal Sadasivan Nair, Proteomic investigation of Trimeresurus malabaricus venom and its comparative functional analysis using Daboia Russelii venom, SnakeSymp-Snake venom research and snakebite therapy, Centre for Cellular and Molecular Biology, Hyderabad, India, December 1-3, 2017.

Year : 2013

Natural Product Mediated Modulation of a Russell’s Viper Metalloprotease Fibrinogenolytic Activity

Cite this Research Publication : A. Alangode, Reick, M., Dr. Martin Reick, and Nair., B., “Natural Product Mediated Modulation of a Russell's Viper Metalloprotease Fibrinogenolytic Activity”, Elsevier Publications. 2013.

Publisher : Elsevier Publications

Awards and Honors
  • Qualified BET- 2010 DBT-JRF examination.
  • “Publication Merit Award” under Amrita Innovation and Research Awards 2021, Amrita Vishwa Vidyapeetham.
Research Projects
  • Modulation of fibrinogenolytic metalloproteinases in Russell’s viper venom using natural products and analogs.
  • Development of peptide inhibitors against Russell’s viper venom metalloproteinases.
  • Functional studies on venom toxins from Malabar Pit viper.
Education
  • M. Sc. Biotechnology, Amrita Vishwa Vidyapeetham, 2009.
  • B. Sc. Zoology, St. Teresas College, Cochin, 2006
Teachings
1. BIO207 – IMMUNOLOGY – BSc Biotechnology and Microbiology – Fourth Semester.
2. BIO282 – Immunology Lab – BSc Biotechnology and Microbiology – Fourth Semester.
3. BIO281 – Cell and Molecular Biology – BSc Biotechnology and Microbiology – Third Semester
4. AVP201 – Amrita Value Program – I – BSc Microbiology – Third Semester.
5 AVP211 – Amrita Value Program -II – BSc MIcrobiology – Fourth Semester.
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