Publication Type : Journal Article
Publisher : Elsevier
Source : Tetrahedron Letters, 2016
Campus : Amritapuri
School : School of Biotechnology
Verified : No
Year : 2016
Abstract : The glycolate alkylation approach for the total synthesis of 8-O.6′ and 8-O.4′-neolignans has been optimized affording the natural products with high overall yields and excellent stereoselectivity. The developed approach can be further utilized towards the synthesis of many natural and unnatural neolignans. This is the first approach for the synthesis of neolignans using asymmetric glycolate alkylation approach.
Cite this Research Publication : Mukesh Gangar, Mangilal Chouhan, Sandeep Goyal, Harikrishnan M., R. Chandran, Avinash Ittuvetil and Vipin A. Nair "Asymmetric glycolate alkylation approach towards the total synthesis of 8-O-6ꞌ and 8-O-4ꞌ neolignans", Tetrahedron Letters 2016, 57, 5931-5934