Qualification: 
MSc
rejithamolr@am.amrita.edu
Phone: 
9746753452

Rejithamol R, received her M. Sc. degree in Organic Chemistry from M. G. University campus, Kottayam in 2009. She then worked as a Project Assistant at the Regional Research Laboratory (now NIIST), Trivandrum in the area of organic synthesis for two years and joined the Department of Chemistry at Amrita School of Arts & Sciences, Amritapuri Campus in 2013.

She is currently doing Ph.D in the area of electrochemical sensors. Her research interests include fabrication of electrochemical sensors for biomolecules like aminoacids, steroids.

ONGOING RESEARCH 

  • Fabrication of Enzymatic and Non-Enzymatic Biosensors : Currently our group was engaged in the fabrication of cholesterol biosensors by the conventional way of modifying the electrodes and to develop both enzymatic and non-enzymatic cholesterol biosensors. This fabricated cholesterol biosensor provides a new platform for routine analysis of cholesterol in human blood serum samples
     
  • • Multicomponent reactions for the synthesis of small organic molecules : Carbon-carbon and carbon-heteroatom bond-forming reactions are central to organic synthesis. Different types of reactions such as polar, pericyclic, and radical reactions have been employed by organic chemists for the construction of carbon-carbon and carbon-heteroatom bonds. Among various intermediates involved in polar reactions, a class of potentially useful dipolar species, viz., zwitterions resulting from the addition of nucleophiles to activated π- systems have been of interest to our research group.
     

Publications

Publication Type: Journal Article

Year of Publication Title

2018

R. Rejithamol, Dr. Beena S., A Santhy, and Asha B Nair, “Synthesis, Characterization and Photophysical Properties of Benzylidene-Fluorene Derivatives”, International Conference on Materials Processing and Characterization, vol. 5, no. 9, pp. 17694-17698, 2018.[Abstract]


A convenient and rapid method for the synthesis of benzylidene-fluorene from aromatic aldehydes and fluorene in presence of 1, 8-diazobicyclo [5,4,0] undec-7-ene (DBU) as an organic catalyst at room temperature giving good yields, short reaction time and easy isolation. Fluorene based π-conjugated organic compounds have found dominant usance that bring about them deserved entrant for utilizations in organic optoelectronic devices and chemical sensors. The report high points an approach to synthesize these materials and to study the photophysical properties

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2018

A Santhy and Rejithamol, R., “Phosphorus species in core sediment and its relation with sediment characteristics of paravur estuary, south west coast of India”, 2018Rasayan Journal of chemistry, vol. 11, pp. 1067 - 1073 , 2018.[Abstract]


The core sediment from two distinct zones of the Paravur estuary, one from the sea water influenced western region and other from the river water influenced eastern region were selected for estimating the different species of phosphorus. The concentration of different species of phosphorus along with iron, organic carbon and textural quality from different sediment depths of the above two locations were investigated. The average value of total phosphorus was found to be higher in fresh water influenced region than marine influenced region. Total phosphorus shows a strong positive correlation with organic carbon in both regions

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2017

R. Rejithamol, K. Aparna, S. Swetha, A. Gayathri, and S. Jisha, “A facile synthesis of α-hydrazino ketones from 1,3-dicarbonyl compounds using 1,8-diazobicyclo[5.4.0]undec-7-ene (DBU) as organic catalyst”, Asian Journal of Chemistry, vol. 29, pp. 1963-1965, 2017.[Abstract]


A convenient and rapid method for the synthesis of α-hydrazino ketones from 1,3-dicarbonyl compounds and diethyl azodicarboxylate in presence of 1,8-diazobicyclo[5.4.0]undec-7-ene as an organic catalyst at room temperature giving good yields, short reaction time and easy isolation. © 2017, Chemical Publishing Co. All rights reserved.

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2012

Vijay Nair, Anu Jose, K. C. Seetha Lakshmi, Rejithamol, R., and Eringathodi Suresh, “A facile four component protocol for the synthesis of dihydropyridine derivatives”, Org. Biomol. Chem., vol. 10, pp. 7747-7752, 2012.[Abstract]


An efficient one pot synthesis of dihydropyridine derivatives employing the transient zwitterions generated from aniline and allenoates is described. More »»

2011

R. Rejithamol, Beneesh Pattoorpad Babu, and Vijay Nair, “A facile Multicomponent Reaction Involving Isoquinoline, Dimethylallene Dicarboxylate and 2-oxo-1H-Indole-3-Ylidenes”, Synthesis, 2011.[Abstract]


Transient zwitterions generated from dimethyl allenedi-carboxylate and isoquinoline were successfully intercepted with 2oxo-IH-indol-3-ylidenes to result in a facile multicomponent reaction under mild conditions. More »»

2011

Vijay Nair, C. R. Sinu, Rejithamol, R., K. C. Seetha Lakshmi, and Eringathodi Suresh, “A novel NHC-catalyzed transformation of 2H-chromene-3-carboxaldehydes to 3-methyl-2H-chromen-2-ones”, Org. Biomol. Chem., vol. 9, pp. 5511-5514, 2011.[Abstract]


An unexpected transformation of 2H-chromene-3-carboxaldehydes to coumarin derivatives{,} mediated by NHC{,} is reported. More »»

Publication Type: Conference Paper

Year of Publication Title

2017

Dr. Beena S., A Santhy, R Vidya, P Uma Sankar, and Rejithamol, R., “Clopidogrel-tetralodo mercurate ion association immobilized PVC membrane sensor for the determination of clopidogrel in pharmaceutical formulations”, in 2017 International Conference on Technological Advancements in Power and Energy (TAP Energy), Kollam, India, 2017.[Abstract]


Fabrication of the PVC membrane sensor incorporating clopidogrel-tetraido mercurate as an electro active material for the determination of clopidogrel bisulphate is demonstrated. Sensor matrix having a composition of PVC 32%, ion association 2.5% and Di-n-butyl phthalate 56.5 % showed best nernstian behavior in the concentration range 1×10 -2 -1×10 -7 M with a lower detection limit of 2.9 × 10 -8 M. Working pH range and response time was found to be 1.8-4.0 and 5s respectively. The sensor was fruitfully utilized for the quantification of clopidogrel from Clopilet tablets. Comparative studies on the various parameters that depend on the performance characteristics of the present sensor with that of the literature reports were also included.

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2014

R. Rejithamol and Dr. G Vijay Nair, “A Novel Multicomponent Reaction Involving Isoquinoline-Allenoate Zwitterion for the Synthesis of Spiro[indoline-3,2’-pyrido[2,1- a]isoquinoline]-3’-carboxylates”, in 16th CRSI National symposium in chemistry, 2014.

2014

Surya Bhaskar, Reshma G R, and Rejithamol, R., “DBU CATALYZED α- AMINATION OF 1, 3-DICARBONYL COMPOUNDS”, in National symposium on transcending frontiers in organic chemistry, 2014.

Publication Type: Conference Proceedings

Year of Publication Title

2014

Surya Bhaskar, Reshma G R, and Rejithamol, R., “DBU CATALYZED α- AMINATION OF 1,3-DICARBONYL COMPOUNDS(Poster)”, National Symposium on Transcending Frontiers In Organic Chemistry. NIIST Trivandrum , 2014.

Faculty Research Interest: