Qualification: 
MSc
Email: 
rejithamolr@am.amrita.edu
Phone: 
9746753452

Rejithamol R. received her M. Sc. degree in Organic Chemistry from M. G. University campus, Kottayam in 2009. She then worked as a Project Assistant at the Regional Research Laboratory (now NIIST), Trivandrum in the area of organic synthesis for two years and joined the Department of Chemistry at Amrita School of Arts & Sciences, Amritapuri Campus in 2013.

She is currently doing Ph.D in the area of electrochemical sensors. Her research interests include Fabrication of electrochemical sensors for biomolecules like aminoacids, steroids and Heterocyclic synthesis using novel multicomponent reactions.

ONGOING RESEARCH 

  • Fabrication of Non-Enzymatic Biosensors:  Currently our group was engaged in the fabrication of cholesterol biosensors by the conventional way of modifying the electrodes and to develop both enzymatic and non-enzymatic cholesterol biosensors. This fabricated cholesterol biosensor provides a new platform for routine analysis of cholesterol in human blood serum samples.
     
  • DBU CATALYZED Α- AMINATION OF 1,3-DICARBONYL COMPOUNDS: Carbon-carbon and carbon-heteroatom bond-forming reactions are central to organic synthesis. The electrophilic α- amination of carbonyl compounds is widely used for the prepration of natural or unnatural α- aminoacids and α- aminoalcohols. Aminating agents such as azidodicarboxylates, nitroso compounds or oxaziridines are typically used as electrophilic nitrogen source. The addition of β-keto esters to azodicarboxylates is one of the preferred method for electrophilic amination. We would like to do α-amination of some 1,3-dicarbonyl compounds using BBU as a base and the annulations of the aminated product using simple Lewis acids as catalyst.
     

Publications

Publication Type: Journal Article

Year of Publication Publication Type Title

2017

Journal Article

R. Rejithamol, Aparna, K., Swetha, S., Gayathri, A., and Jisha, S., “A facile synthesis of α-hydrazino ketones from 1,3-dicarbonyl compounds using 1,8-diazobicyclo[5.4.0]undec-7-ene (DBU) as organic catalyst”, Asian Journal of Chemistry, vol. 29, pp. 1963-1965, 2017.[Abstract]


A convenient and rapid method for the synthesis of α-hydrazino ketones from 1,3-dicarbonyl compounds and diethyl azodicarboxylate in presence of 1,8-diazobicyclo[5.4.0]undec-7-ene as an organic catalyst at room temperature giving good yields, short reaction time and easy isolation. © 2017, Chemical Publishing Co. All rights reserved.

More »»

2012

Journal Article

V. Nair, Jose, A., Lakshmi, K. C. Seetha, Rejithamol, R., and Suresh, E., “A facile four component protocol for the synthesis of dihydropyridine derivatives”, Org. Biomol. Chem., vol. 10, pp. 7747-7752, 2012.[Abstract]


An efficient one pot synthesis of dihydropyridine derivatives employing the transient zwitterions generated from aniline and allenoates is described. More »»

2011

Journal Article

V. Nair, Sinu, C. R., Rejithamol, R., Lakshmi, K. C. Seetha, and Suresh, E., “A novel NHC-catalyzed transformation of 2H-chromene-3-carboxaldehydes to 3-methyl-2H-chromen-2-ones”, Org. Biomol. Chem., vol. 9, pp. 5511-5514, 2011.[Abstract]


An unexpected transformation of 2H-chromene-3-carboxaldehydes to coumarin derivatives{,} mediated by NHC{,} is reported. More »»

2011

Journal Article

R. Rejithamol, Babu, B. Pattoorpad, and Nair, V., “A facile Multicomponent Reaction Involving Isoquinoline, Dimethylallene Dicarboxylate and 2-oxo-1H-Indole-3-Ylidenes”, Synthesis, 2011.[Abstract]


Transient zwitterions generated from dimethyl allenedi-carboxylate and isoquinoline were successfully intercepted with 2oxo-IH-indol-3-ylidenes to result in a facile multicomponent reaction under mild conditions. More »»

Publication Type: Conference Proceedings

Year of Publication Publication Type Title

2014

Conference Proceedings

S. Bhaskar, R, R. G., and Rejithamol, R., “DBU CATALYZED α- AMINATION OF 1,3-DICARBONYL COMPOUNDS(Poster)”, National Symposium on Transcending Frontiers In Organic Chemistry. NIIST Trivandrum , 2014.

Faculty Research Interest: 
207
PROGRAMS
OFFERED
5
AMRITA
CAMPUSES
15
CONSTITUENT
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A
GRADE BY
NAAC, MHRD
9th
RANK(INDIA):
NIRF 2017
150+
INTERNATIONAL
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